Terazosin hydrochloride dihydrate

Basic Information

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CAS Number

70024-40-7

Molecular Formula

C19H30ClN5O6

Molecular Weight

459.93 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

274°C

SMILES

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COC1=C(C=C2C(=C1)C(=NC(=N2)N3CCN(CC3)C(=O)C4CCCO4)N)OC.O.O.Cl

InChI

InChI=1S/C19H25N5O4.ClH.2H2O/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14;;;/h10-11,14H,3-9H2,1-2H3,(H2,20,21,22);1H;2*1H2

InChIKey

NZMOFYDMGFQZLS-UHFFFAOYSA-N

LogP

-0.17080000000000034

Topological Polar Surface Area

166.04000000000002 Å²

Hydrogen Bond Donor/Acceptor

6 / 11

Complexity

544

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Toxicity

LD50 in male, female rats (mg/kg): 277, 293 i.v. (Fort)

Synonyms & References

English

NZMOFYDMGFQZLS-UHFFFAOYSA-N
Heitrin
Vicard
Dysalfa
Urodie
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetrahydro-2-furanyl)carbonyl)piperazine HCl 2H2O
Terazosin Abbot
TERAZOSIN HYDROCHLORIDE DIHYDRATE [MI]
SW196457-4
Uroflo
NSC-759168
Hydracin
TERAZOSIN HYDROCHLORIDE HYDRATE [JAN]
Sinalfa
Hytrine
TERAZOSIN HYDROCHLORIDE [ORANGE BOOK]
Terazosin for system suitability, European Pharmacopoeia (EP) Reference Standard
UNII-D32S14F082
Hitrin
CHEMBL3989562
methanone hydrochloride dihydrate
ABT-975
Hytrinex
TERAZOSIN HYDROCHLORIDE [USP MONOGRAPH]
Terazosin Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material
BT164459
70024-40-7 (HCl)
Terazosin hydrochloride, United States Pharmacopeia (USP) Reference Standard
MFCD00941408
Terazosin monohydrochloride dihydrate
Itrin

MDL Number

MFCD00941408

FAQ

What is Terazosin hydrochloride dihydrate (CAS: 70024-40-7)?

Terazosin hydrochloride dihydrate is a pharmaceutical compound used to treat hypertension and benign prostatic hyperplasia. Its chemical formula is C15H18N2O·2HCl·2H2O. This compound is a white crystalline powder with a bitter taste and is soluble in water.

What are the main uses of Terazosin hydrochloride dihydrate (CAS: 70024-40-7)?

Terazosin hydrochloride dihydrate is primarily used in the treatment of hypertension and benign prostatic hyperplasia. It works by relaxing smooth muscles, which can help reduce blood pressure and improve urinary flow in patients with enlarged prostates.

Is Terazosin hydrochloride dihydrate (CAS: 70024-40-7) safe?

Terazosin hydrochloride dihydrate is generally safe when used as prescribed. However, it can cause side effects such as dizziness, fainting, and hypotension. It is important to follow the recommended dosage and consult a healthcare provider if any adverse reactions occur. Storage and handling should comply with standard pharmaceutical safety guidelines.

How should Terazosin hydrochloride dihydrate (CAS: 70024-40-7) be stored?

Terazosin hydrochloride dihydrate should be stored at temperatures below 25°C (77°F) in a tightly closed container to protect from moisture and light. It should be kept out of reach of children and pets. Avoid exposure to high temperatures and direct sunlight. Keep in a cool, dry place away from strong acids and bases.