4-methylbenzene-1-sulfonamide

Basic Information

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CAS Number

70-55-3

Molecular Formula

C7H9NO2S

Molecular Weight

171.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

134-137 °C

Boiling Point

214°C/9.98mmHg

Density

1.2495 (rough estimate)

Water Solubility

0.32 g/100 mL (25 º C)

Solubility

DMSO: soluble

Refractive Index

1.6100 (estimate)

SMILES

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Cc1ccc(cc1)S(=O)(=O)N

InChI

InChI=1S/C7H9NO2S/c1-6-2-4-7(5-3-6)11(8,9)10/h2-5H,1H3,(H2,8,9,10)

InChIKey

LMYRWZFENFIFIT-UHFFFAOYSA-N

LogP

0.6424200000000001

Topological Polar Surface Area

60.16 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

209

Safety Information

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GHS Hazard Pictograms

H319

Hazard Statement

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Sensitiveness

对湿度敏感

Synonyms & References

English

4-Methylbenzenesulfonamide
PTSA
PASAM
o-Toluenesulphonamide(OTSA)
p-Toluenesulphonamide
P-TOLUENE SULFONAMIDE
P-toluene sulfonylamine
Toluene-4-sulphonamide
P-Toluene Sulfonamide (PTSA)
4-Methylbenzene-1-sulfonamide
4-Toluenesulfonamide
4-Tolylsulfonamide
p-Toluenesulfonylamide
Mixed O
Ortho Para-Toluene Sulfonamide
Para-Toluene Sulfonamide(PTSA)
PTSA (P-Toluenesulfonamide)
对甲苯磺酰胺
4-Toluene sulfonamide
P-TOLUENESULFONAMIDE
Tosylamide
p-Tosylamide
Toluene-4-sulfonamide
Benzenesulfonamide, 4-methyl-
p-Tolylsulfonamide
Tolylsulfonamide
p-Toluenesulfamide
p-Methylbenzenesulfonamide
Toluene-p-sulphonamide
para-Toluenesulfonamide
4-Toluenesulfanamide

MDL Number

MFCD00011692

Customs Code

2935009090

FAQ

What is 4-methylbenzene-1-sulfonamide (CAS: 70-55-3)?

4-Methylbenzene-1-sulfonamide, also known as 4-methyl-N-phthalimido sulfonamide, is an organic compound with the chemical formula C8H9NO2S. It is a white crystalline solid with a pungent odor, commonly used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. Its structure includes a sulfonamide group attached to a benzene ring with a methyl substituent.

What are the main uses of 4-methylbenzene-1-sulfonamide (CAS: 70-55-3)?

4-Methylbenzene-1-sulfonamide is primarily used in the pharmaceutical industry as a building block for drug development. It also finds applications in the synthesis of dyes, pesticides, and other organic chemicals. In research settings, it serves as a versatile intermediate for creating derivatives with specific functional groups, aiding in the development of new materials and compounds.

Is 4-methylbenzene-1-sulfonamide (CAS: 70-55-3) safe?

4-Methylbenzene-1-sulfonamide is generally considered safe when handled properly. However, it may cause irritation to the skin, eyes, and respiratory system. Safety data sheets (SDS) recommend using appropriate personal protective equipment (PPE), such as gloves and goggles, and ensuring good ventilation during handling. It should be stored away from incompatible materials and in compliance with OSHA and EPA standards.

How should 4-methylbenzene-1-sulfonamide (CAS: 70-55-3) be stored?

4-Methylbenzene-1-sulfonamide should be stored in a cool, dry place, away from direct sunlight. It is best kept in a sealed container to prevent moisture absorption and maintain stability. Storage conditions should be below 25°C and with humidity levels below 60% to avoid degradation. Always store in a well-ventilated area and away from incompatible substances.