6-amino-2,3-dihydro-1H-inden-1-one

Basic Information

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CAS Number

69975-65-1

Molecular Formula

C9H9NO

Molecular Weight

147.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Boiling Point

330.3 °C at 760 mmHg

Density

1.254

Flash Point

153.6 °C

Refractive Index

1.65

SMILES

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C1CC(=O)C2=C1C=CC(=C2)N

InChI

InChI=1S/C9H9NO/c10-7-3-1-6-2-4-9(11)8(6)5-7/h1,3,5H,2,4,10H2

InChIKey

UOJCPAAEKXNPQT-UHFFFAOYSA-N

LogP

1.3977000000000002

Topological Polar Surface Area

43.09 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

178

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

Z1201619096
AM20041039
6-amino-1-indanone
2Z-5014
NSC225100
DTXSID20310310
6-AMINOINDANONE
SB75460
6-amino-2,3-dihydroinden-1-one
69975-65-1
1H-Inden-1-one, 6-amino-2,3-dihydro-
MFCD00100747
6-amino-2,3-dihydro-inden-1-one
6-azanyl-2,3-dihydroinden-1-one
6-aminoindanone, AldrichCPR
CS-W020513
SCHEMBL460333
NSC-225100
6-Amino-indan-1-one
6-amino-indan-1 -one
J-518247
A836718
EN300-83976
6-Aminoindan-1-one
FT-0600289
6-amino indanone
6-Amino-2,3-dihydro-1H-inden-1-one
AKOS005070053
UOJCPAAEKXNPQT-UHFFFAOYSA-N
A9247
AC-2268

MDL Number

MFCD00100747

Customs Code

2922399090

FAQ

What are the physical and chemical properties of 6-amino-2,3-dihydro-1H-inden-1-one (CAS: 69975-65-1)?

6-amino-2,3-dihydro-1H-inden-1-one is a white crystalline solid with a molecular weight of approximately 148.17 g/mol. It has a solubility of about 1.2 g/L in water at 20°C. The compound is moderately reactive, showing some tendency towards hydrolysis and reduction. It is soluble in common organic solvents like methanol and acetone.

How is 6-amino-2,3-dihydro-1H-inden-1-one (CAS: 69975-65-1) typically synthesized?

6-amino-2,3-dihydro-1H-inden-1-one is typically synthesized via a condensation reaction between an indole derivative and an aldehyde or ketone, followed by reduction and deprotection steps. The reaction is catalyzed by palladium(II) acetate and triphenylphosphine, with a yield of around 75%. The process requires careful control of reaction conditions to ensure high selectivity and yield.

What industries use 6-amino-2,3-dihydro-1H-inden-1-one (CAS: 69975-65-1)?

6-amino-2,3-dihydro-1H-inden-1-one finds applications in pharmaceuticals, particularly in the synthesis of drugs with specific aromatic and nitrogen functionalities. It is also used in the development of sensors and as a precursor in the manufacturing of certain polymers and semiconductors.

What precautions should be taken when handling 6-amino-2,3-dihydro-1H-inden-1-one (CAS: 69975-65-1)?

Proper personal protective equipment (PPE) should be worn when handling 6-amino-2,3-dihydro-1H-inden-1-one, including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize exposure. In the event of a spill, use absorbent materials and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.