Cefodizime | CAS No. 69739-16-8

Cefodizime

Basic Information

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CAS Number

69739-16-8

Molecular Formula

C20H20N6O7S4

Molecular Weight

584.7 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

204-223°C

Density

1.86

Refractive Index

1.851

Specific Rotation

D25 -55.9°

SMILES

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CC1=C(SC(=N1)SCC2=C(N3C(C(C3=O)NC(=O)C(=NOC)C4=CSC(=N4)N)SC2)C(=O)O)CC(=O)O

InChI

InChI=1S/C20H20N6O7S4/c1-7-10(3-11(27)28)37-20(22-7)36-5-8-4-34-17-13(16(30)26(17)14(8)18(31)32)24-15(29)12(25-33-2)9-6-35-19(21)23-9/h6,13,17H,3-5H2,1-2H3,(H2,21,23)(H,24,29)(H,27,28)(H,31,32)/b25-12-/t13-,17-/m1/s1

InChIKey

XDZKBRJLTGRPSS-BGZQYGJUSA-N

LogP

0.9987199999999994

pKa

pK1 2.85; pK2 3.37; pK3 4.18(at 25℃)

Topological Polar Surface Area

197.39999999999998 Å²

Hydrogen Bond Donor/Acceptor

5 / 13

Complexity

1030

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

DB13470
CS-0028575
Neucef
Cefodizime (INN)
HY-108402
Cefodizme
Timecef
SCHEMBL151101
HR 221 [AS SODIUM]
(6R,7R)-7-{[(22Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CHEBI:63214
CDZM
HR 221
S 77 1221 B [AS SODIUM]
Cefodizime
CEFODIZIME DISODIUM
UNII-Z31298J4HQ
Cefodizime [INN:BAN]
CHEMBL2303613
HR 221 FREE ACID
Z31298J4HQ
(6R,7R)-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-7-{[(2Z)-1-hydroxy-2-(2-imino-2,3-dihydro-1,3-thiazol-4-yl)-2-(methoxyimino)ethylidene]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
AKOS040741529
Cefodizima [INN-Spanish]
S-77-1221B
HR-221 [As Sodium]
Modivid
1ST12029
7-[[(2E)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
THR-221 [As Sodium]
S 77 1221 B FREE ACID

MDL Number

MFCD00864926

FAQ

What regulatory guidelines apply to Cefodizime (CAS: 69739-16-8)?

Cefodizime (CAS: 69739-16-8) is subject to various regulatory guidelines such as GHS classification for hazardous materials, REACH regulations in the European Union, and FDA/EPA requirements for drug and chemical safety. Manufacturers and handlers must comply with local and international standards to ensure safe use and disposal.

Are there alternatives to Cefodizime (CAS: 69739-16-8) in synthesis?

There are several alternatives to Cefodizime (CAS: 69739-16-8) in synthesis, including other cephalosporin antibiotics and their isomers. Common alternative reagents and substitutes include cefuroxime and cefaclor, which are structurally similar and can be used in similar applications.

What is the market or research trend for Cefodizime (CAS: 69739-16-8)?

The market trend for Cefodizime (CAS: 69739-16-8) reflects a stable demand due to its effectiveness in treating various bacterial infections. Research focuses on understanding its mechanism of action, potential for combination therapies, and exploring its use in developing countries where treatment options are limited.

How should waste containing Cefodizime (CAS: 69739-16-8) be handled?

Waste containing Cefodizime (CAS: 69739-16-8) should be collected and handled according to local waste management regulations. Typically, it should be incinerated or disposed of through professional waste disposal services to ensure environmental safety. Proper precautions should be taken to prevent contamination and ensure the waste is managed in an environmentally responsible manner.