2'-TBDMS-Bz-rA

Basic Information

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CAS Number

69504-07-0

Molecular Formula

C23H31N5O5Si

Molecular Weight

485.62 g/mol

Basic Physical Properties

Density

1.33±0.1 g/cm3 (20 ºC 760 Torr),

Solubility

Insuluble (4.7E-4 g/L) (25 ºC),

SMILES

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CC(C)(C)[Si](C)(C)OC1C(C(OC1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)CO)O

InChI

InChI=1S/C23H31N5O5Si/c1-23(2,3)34(4,5)33-18-17(30)15(11-29)32-22(18)28-13-26-16-19(24-12-25-20(16)28)27-21(31)14-9-7-6-8-10-14/h6-10,12-13,15,17-18,22,29-30H,11H2,1-5H3,(H,24,25,27,31)/t15-,17-,18-,22-/m1/s1

InChIKey

XZQPQOSSEMTXOW-UVLLPENVSA-N

LogP

2.719600000000001

Topological Polar Surface Area

131.62 Å²

Hydrogen Bond Donor/Acceptor

3 / 10

Complexity

716

Synonyms & References

English

J-700355
N-[9-[(2R,3R,4R,5R)-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]benzamide
SCHEMBL6402239
AC-32349
N-{9-[(2R,3R,4R,5R)-3-[(tert-butyldimethylsilyl)oxy]-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-9H-purin-6-yl}benzamide
N-(9-((2R,3R,4R,5R)-3-((tert-Butyldimethylsilyl)oxy)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide
2'-TBDMS-Bz-rA
N6-Benzoyl-2'-O-tert-butyldimethylsilyladenosine
69504-07-0
2'-TBDMS-BZ-RA
N6-benzoyl-2'-O-(tert-butyldiMethylsilyl)adenosine
2-TBDMS-BZ-RA
N-Benzoyl-2'-O-(tert-butyldimethylsilyl)adenosine

MDL Number

MFCD28134644

FAQ

What is 2'-TBDMS-Bz-rA (CAS: 69504-07-0)?

2'-TBDMS-Bz-rA (CAS: 69504-07-0) is a modified nucleoside derivative, specifically a 2'-O-benzoyl-4'-thio-deoxy-adenosine with a tert-butyldimethylsilyl (TBDMS) protecting group. It is used as a substrate in DNA synthesis and modification.

What are the main uses of 2'-TBDMS-Bz-rA (CAS: 69504-07-0)?

2'-TBDMS-Bz-rA (CAS: 69504-07-0) is primarily used in nucleotide synthesis and DNA modification, especially in the production of modified oligonucleotides for research and therapeutic applications.

Is 2'-TBDMS-Bz-rA (CAS: 69504-07-0) safe?

2'-TBDMS-Bz-rA (CAS: 69504-07-0) is considered safe when handled with appropriate precautions. It is important to follow all recommended safety guidelines, including the use of gloves and proper ventilation.

How should 2'-TBDMS-Bz-rA (CAS: 69504-07-0) be stored?

2'-TBDMS-Bz-rA (CAS: 69504-07-0) should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent degradation.