5-Iodo-2-methylpyridine

Basic Information

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CAS Number

695-17-0

Molecular Formula

C6H6IN

Molecular Weight

219.03 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

48-49 ºC

Boiling Point

218.6°C at 760 mmHg

Density

1.810

Flash Point

86 ºC

SMILES

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CC1=NC=C(C=C1)I

InChI

InChI=1S/C6H6IN/c1-5-2-3-6(7)4-8-5/h2-4H,1H3

InChIKey

FMOQWAKITQNDFW-UHFFFAOYSA-N

LogP

1.9946199999999998

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

74.9

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

5-Iodo-2-methylpyridine
AS-18508
AKOS015842570
5-Iodo-2-picoline
AMY19858
3-iodo-6-methylpyridine
SCHEMBL3403753
FT-0646487
A836524
CS-W022395
695-17-0
Pyridine, 5-iodo-2-methyl-
DTXSID10467983
5-iodo-2-methyl-pyridine
FMOQWAKITQNDFW-UHFFFAOYSA-N
EN300-156108
SY023080
2-Methyl-5-iodopyridine
MFCD07437990
2-METHYL-5-IODOPYRIDINE
Pyridine,5-iodo-2-methyl-
PubChem6698
5-iodanyl-2-methyl-pyridine
2-METHYL-5-IODO PYRIDINE
VP10361
BC228957
AB0026296
ST2418798
AB1005342
W7929

MDL Number

MFCD07437990

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 5-Iodo-2-methylpyridine (CAS: 695-17-0)?

5-Iodo-2-methylpyridine (5-iodo-2-methylpyridine, CAS: 695-17-0) is a crystalline solid with a molecular weight of approximately 239.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. The compound is relatively stable but can react with reducing agents. It is a potent antimicrobial agent and exhibits high reactivity with nucleophiles.

How is 5-Iodo-2-methylpyridine (CAS: 695-17-0) typically synthesized?

5-Iodo-2-methylpyridine is typically synthesized via the iodination of 2-methylpyridine using iodine in the presence of a Lewis acid catalyst, such as aluminum chloride. The reaction is selective and yields a pure product with high efficiency. The process involves stirring the mixture at room temperature and then purifying the product via recrystallization.

What industries use 5-Iodo-2-methylpyridine (CAS: 695-17-0)?

5-Iodo-2-methylpyridine (CAS: 695-17-0) is primarily used in the pharmaceutical industry for the synthesis of antimicrobial agents. It is also used in the production of various organic compounds and materials, including polymers and semiconductors. Its antimicrobial properties make it valuable in the development of new drugs and disinfectants.

What precautions should be taken when handling 5-Iodo-2-methylpyridine (CAS: 695-17-0)?

When handling 5-Iodo-2-methylpyridine (CAS: 695-17-0), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. It should be handled in a well-ventilated area or a fume hood. Spills should be managed by carefully collecting and disposing of the material according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.