Atorvastatin Impurity 24

Basic Information

View in Editor

CAS Number

693793-82-7

Molecular Formula

C26H23F2NO3

Molecular Weight

435.47 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

View in Editor

CC(C)C(=O)C(C(c1ccc(cc1)F)C(=O)c2ccc(cc2)F)C(=O)Nc3ccccc3

InChI

InChI=1S/C26H23F2NO3/c1-16(2)24(30)23(26(32)29-21-6-4-3-5-7-21)22(17-8-12-19(27)13-9-17)25(31)18-10-14-20(28)15-11-18/h3-16,22-23H,1-2H3,(H,29,32)

InChIKey

KUEDWDDLRXOHDM-UHFFFAOYSA-N

LogP

5.411300000000004

Topological Polar Surface Area

63.24 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Synonyms & References

English

4-Fluoro-β-(4-fluorophenyl)-α-(2-methyl-1-oxopropyl)-γ-oxo-N-phenylbenzenebutanamide

FAQ

What are the physical and chemical properties of Atorvastatin Impurity 24 (CAS: 693793-82-7)?

Atorvastatin Impurity 24 (CAS: 693793-82-7) is a crystalline compound with a molecular weight of approximately 414.49 g/mol. It has a low solubility in water (0.02 g/L) but is more soluble in organic solvents like methanol and ethanol. Chemically, it is less reactive than its parent compound, Atorvastatin, and exhibits typical behavior for impurities in the class of statins.

How is Atorvastatin Impurity 24 (CAS: 693793-82-7) typically synthesized?

Atorvastatin Impurity 24 (CAS: 693793-82-7) is synthesized through various organic synthesis routes involving stereoselective reactions. Commonly, it is produced via hydrogenation of a key intermediate, followed by selective functional group manipulations. The process often utilizes transition metal catalysts and employs high-pressure hydrogenation techniques to achieve the desired stereochemistry and yield.

What industries use Atorvastatin Impurity 24 (CAS: 693793-82-7)?

Atorvastatin Impurity 24 (CAS: 693793-82-7) is primarily used in the pharmaceutical industry, where it serves as an intermediate in the synthesis of Atorvastatin, a lipid-lowering medication. It is also of interest in academic and research settings for studying impurities and their effects in drug development.

What precautions should be taken when handling Atorvastatin Impurity 24 (CAS: 693793-82-7)?

When handling Atorvastatin Impurity 24 (CAS: 693793-82-7), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Handle in a well-ventilated area or under a fume hood. Store the compound in a cool, dry place away from direct sunlight. In case of a spill, follow standard laboratory procedures for hazardous materials. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.