(2,6-Dimethyl-3-pyridinyl)boronic acid

Basic Information

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CAS Number

693774-55-9

Molecular Formula

C7H10BNO2

Molecular Weight

150.97 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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B(C1=C(N=C(C=C1)C)C)(O)O

InChI

InChI=1S/C7H10BNO2/c1-5-3-4-7(8(10)11)6(2)9-5/h3-4,10-11H,1-2H3

InChIKey

OZGKXVIJOMDZCP-UHFFFAOYSA-N

LogP

-0.6217600000000001

Topological Polar Surface Area

53.35 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

132

Synonyms & References

English

2 pound not6-Dimethylpyridin-3-ylboronic acid
693774-55-9
2,6-Dimethylpyridin-3-ylboronicacid
AMY8036
OZGKXVIJOMDZCP-UHFFFAOYSA-N
AB41961
(2,6-dimethylpyridin-3-yl)boronic Acid
(2,6-dimethyl-3-pyridinyl)boronic acid
A836459
AC-33301
2,6-Domethylpyridine-3-boronic acid
2,6-Dimethylpyridin-3-ylboronic acid
SY029371
2,6-Dimethylpyridine-3-boronicacid
CS-W020654
EN300-316361
FD10078
AKOS006285112
FT-0646484
SCHEMBL489376
Boronic acid, (2,6-dimethyl-3-pyridinyl)-
DTXSID60376733
B-(2,6-Dimethyl-3-pyridinyl)-boronicacid
2,6-DIMETHYLPYRIDINE-3-BORONIC ACID
MFCD07437925
2,6-dimethyl-pyridine-3-boronic acid, AldrichCPR
B-(2,6-Dimethyl-3-pyridinyl)boronic acid
DS-12835
(2,6-dimethylpyridin-3-yl)boronic acid
2,6-Dimethylpyridine-3-boronic acid
Boronic acid,B-(2,6-dimethyl-3-pyridinyl)-

MDL Number

MFCD07437925

FAQ

What are the physical and chemical properties of (2,6-Dimethyl-3-pyridinyl)boronic acid (CAS: 693774-55-9)?

(2,6-Dimethyl-3-pyridinyl)boronic acid is a white crystalline solid with a molecular weight of approximately 214.25 g/mol. It has a moderate solubility in organic solvents like ethanol and poor solubility in water. The compound shows limited reactivity, primarily in esterification reactions due to the boronic acid functionality. It is stable under normal conditions but should be stored in a cool, dry place to prevent moisture absorption.

How is (2,6-Dimethyl-3-pyridinyl)boronic acid (CAS: 693774-55-9) typically synthesized?

(2,6-Dimethyl-3-pyridinyl)boronic acid can be synthesized through the reaction of 2,6-dimethylpyridine with boron tribromide in the presence of a Lewis acid catalyst like aluminum trichloride. This method provides a high yield and good selectivity. The reaction proceeds via an electrophilic aromatic substitution followed by a boration step.

What industries use (2,6-Dimethyl-3-pyridinyl)boronic acid (CAS: 693774-55-9)?

(2,6-Dimethyl-3-pyridinyl)boronic acid finds applications in pharmaceuticals for the synthesis of drugs, polymers for advanced material science, and sensors in analytical chemistry. Its use in semiconductors is limited due to its low reactivity, but it is valuable in specific synthetic procedures where boronic acids are required.

What precautions should be taken when handling (2,6-Dimethyl-3-pyridinyl)boronic acid (CAS: 693774-55-9)?

When handling (2,6-Dimethyl-3-pyridinyl)boronic acid, it is important to wear appropriate personal protective equipment (PPE) such as gloves and goggles. Store the compound in a cool, dry place to prevent moisture absorption. Use a fume hood during handling to minimize exposure to vapors. In case of a spill, promptly clean up using appropriate absorbent materials and follow the safety data sheet (SDS) guidelines for proper disposal.