Methyl 4-amino-3-thiophenecarboxylate

Basic Information

View in Editor

CAS Number

69363-85-5

Molecular Formula

C6H7NO2S

Molecular Weight

157.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

SMILES

View in Editor

COC(=O)C1=CSC=C1N

InChI

InChI=1S/C6H7NO2S/c1-9-6(8)4-2-10-3-5(4)7/h2-3H,7H2,1H3

InChIKey

BUFZZXCVOFBHLS-UHFFFAOYSA-N

LogP

1.1169

Topological Polar Surface Area

52.32 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

140

Safety Information

View Safety Information

Hazard Statement

Synonyms & References

English

EN300-144234
PS-4350
FT-0628615
A836452
methyl4-aminothiophene-3-carboxylate
Maybridge1_003924
MFCD00130102
CS-0150758
W-203542
methyl 4-aminothiophen-3-carboxylate
SCHEMBL166467
3-Thiophenecarboxylic acid, 4-amino-, methyl ester
69363-85-5
methyl-4-AMINOTHIOPHENE-3-CARBOXYLATE
SB67092
4-aminothiophene-3-carboxylic acid methyl ester
Maybridge1_003880
AKOS005067072
methyl 4-aminothiophene-3-carboxylate
4-amino-thiophene-3-carboxylic acid methyl ester
4-amino-3-thiophenecarboxylic acid methyl ester
BUFZZXCVOFBHLS-UHFFFAOYSA-N
methyl 4-amino-3-thiophenecarboxylate
3-Amino-4-(methoxycarbonyl)thiophene
methyl 4-amino-3-thiophene carboxylate
P17958
methyl 4-azanylthiophene-3-carboxylate
methyl 4-amino-3-thenoate
HMS552K08
methyl 3-amino-4-thiophenecarboxylate
DTXSID70380588

MDL Number

MFCD00130102

FAQ

What are the physical and chemical properties of Methyl 4-amino-3-thiophenecarboxylate (CAS: 69363-85-5)?

Methyl 4-amino-3-thiophenecarboxylate (CAS: 69363-85-5) is a crystalline solid with a molecular weight of approximately 216.24 g/mol. It is slightly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is a thiophene derivative with an amino group, which makes it reactive towards nucleophiles and can participate in various chemical reactions such as esterification and nucleophilic substitution.

How is Methyl 4-amino-3-thiophenecarboxylate (CAS: 69363-85-5) typically synthesized?

Methyl 4-amino-3-thiophenecarboxylate (CAS: 69363-85-5) can be synthesized by reacting 3-thiophenecarboxylic acid with methylamine in the presence of a catalyst, such as triethylamine. The reaction is typically carried out under mild conditions, and the product can be isolated by recrystallization from an appropriate solvent, yielding a high yield and good purity.

What industries use Methyl 4-amino-3-thiophenecarboxylate (CAS: 69363-85-5)?

Methyl 4-amino-3-thiophenecarboxylate (CAS: 69363-85-5) finds applications in the pharmaceutical industry for the synthesis of certain drugs, particularly those involving thiophene derivatives. It is also used in the polymer industry for the development of novel materials and in the semiconductor industry for the fabrication of thin films and sensors.

What precautions should be taken when handling Methyl 4-amino-3-thiophenecarboxylate (CAS: 69363-85-5)?

When handling Methyl 4-amino-3-thiophenecarboxylate (CAS: 69363-85-5), it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Ensure the use of a fume hood during operations. In case of a spill, neutralize the material with an appropriate base and dispose of it according to local regulations. Always consult the Safety Data Sheet (SDS) for specific handling and disposal instructions.