5-[(E)-2-Bromovinyl]-2'-deoxyuridine

Basic Information

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CAS Number

69304-47-8

Molecular Formula

C11H13BrN2O5

Molecular Weight

333.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

165°C

Boiling Point

382.9°C at 760 mmHg

Density

1.7800 (rough estimate)

Water Solubility

Soluble in water and methanol.

Flash Point

185.4°C

Refractive Index

1.6520 (estimate)

SMILES

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C1C(C(OC1N2C=C(C(=O)NC2=O)C=CBr)CO)O

InChI

InChI=1S/C11H13BrN2O5/c12-2-1-6-4-14(11(18)13-10(6)17)9-3-7(16)8(5-15)19-9/h1-2,4,7-9,15-16H,3,5H2,(H,13,17,18)/b2-1+/t7-,8+,9+/m0/s1

InChIKey

ODZBBRURCPAEIQ-PIXDULNESA-N

LogP

-0.4571

Topological Polar Surface Area

104.54999999999998 Å²

Hydrogen Bond Donor/Acceptor

3 / 7

Complexity

450

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

(E)-5-(2-Bromovinyl)-2'-deoxyuridine
J-700153
LP00175
(E)-5-(2-Bromovinyl)-dUrd
UNII-2M3055079H
Helpin
RP-101
69304-47-8
A-176
CHEMBL31634
SCHEMBL99350
NSC-633770
Uridine, 5-(2-bromoethenyl)-2'-deoxy-, (E)-
BDBM50366681
NSC 633770
CCRIS 2831
Brivudinum
Uridine, 5-[(1E)-2-bromoethenyl]-2'-deoxy-
5-(E)-(2-bromovinyl)-2'-deoxyuridine
HY-13578
Brivudine (INN)
5-[(E)-2-bromoethenyl]-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
SCHEMBL141408
BrVdUrd
CS-6292
Bromovinyldeoxyuridine
D07249
Uridine, 5-(2-bromovinyl)-2'-deoxy-, (E)-
e-5-(2-bromovinyl)-2'-deoxyuridine
5-[(E)-2-bromoethenyl]-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
CAS-69304-47-8

MDL Number

MFCD00058585

FAQ

What regulatory guidelines apply to 5-[(E)-2-Bromovinyl]-2'-deoxyuridine (CAS: 69304-47-8)?

5-[(E)-2-Bromovinyl]-2'-deoxyuridine (CAS: 69304-47-8) must comply with GHS (Globally Harmonized System) classification, REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) regulations, and FDA/EPA guidelines for hazardous substances. Specific requirements include proper labeling, documentation, and handling procedures to ensure worker and environmental safety.

Are there alternatives to 5-[(E)-2-Bromovinyl]-2'-deoxyuridine (CAS: 69304-47-8) in synthesis?

Alternatives to 5-[(E)-2-Bromovinyl]-2'-deoxyuridine (CAS: 69304-47-8) in synthesis include other nucleoside analogs and brominated compounds. Common substitutes include 5-bromouracil and related derivatives. These alternatives may offer similar properties but are chosen based on specific reaction conditions and desired outcomes.

What is the market or research trend for 5-[(E)-2-Bromovinyl]-2'-deoxyuridine (CAS: 69304-47-8)?

The market and research trend for 5-[(E)-2-Bromovinyl]-2'-deoxyuridine (CAS: 69304-47-8) is focused on its use as a potential antiviral and antitumor agent. Recent studies have explored its efficacy in combating viral infections and cancer. The trend indicates increasing interest in developing and optimizing its applications in pharmaceutical and therapeutic fields.

How should waste containing 5-[(E)-2-Bromovinyl]-2'-deoxyuridine (CAS: 69304-47-8) be handled?

Waste containing 5-[(E)-2-Bromovinyl]-2'-deoxyuridine (CAS: 69304-47-8) should be collected in appropriate containers and stored in a secure, well-ventilated area. For disposal, use professional waste disposal services to ensure environmental safety. Follow local regulations and guidelines for hazardous waste management to minimize environmental impact and comply with legal requirements.