4-(Chloromethyl)-2-(3-chlorophenyl)-1,3-thiazole hydrochloride (1:1) | CAS No. 690632-83-8
4-(Chloromethyl)-2-(3-chlorophenyl)-1,3-thiazole hydrochloride (1:1)
Basic Information
CAS Number
690632-83-8
Molecular Formula
C10H8Cl3NS
Molecular Weight
280.61 g/mol
AD
Basic Physical Properties
Melting Point
126 °C
Synonyms & References
English
- AKOS015920416
- 4-(Chloromethyl)-2-(3-chlorophenyl)thiazolehydrochloride
- 4-(chloromethyl)-2-(3-chlorophenyl)thiazole hydrochloride
- 4-(chloromethyl)-2-(3-chlorophenyl)-1,3-thiazole;hydrochloride
- 4-Chloromethyl-2-(3-chloro-phenyl)-thiazole
- 4-chloromethyl-2-(3-chloro-phenyl)-thiazole hcl
- DTXSID80383308
- AC-9363
- FT-0692335
- 4-(Chloromethyl)-2-(3-chlorophenyl)-1,3-thiazole--hydrogen chloride (1/1)
- C10H8Cl3NS
- AS-31412
- 4-(Chloromethyl)-2-(3-chlorophenyl)-thiazole hydrochloride
- MFCD05664422
- 4-(chloromethyl)-2-(3-chlorophenyl)-1,3-thiazole Hydrochloride
- 690632-83-8
- A836344
- 4-(Chloromethyl)-2-(3-chlorophenyl)thiazole hydrochloride
- 4-(Chloromethyl)-2-(3-chlorophenyl)-1,3-thiazole hydrochloride
MDL Number
MFCD05664422
Customs Code
2934100090
FAQ
What are the physical and chemical properties of 4-(Chloromethyl)-2-(3-chlorophenyl)-1,3-thiazole hydrochloride (CAS: 690632-83-8)?
4-(Chloromethyl)-2-(3-chlorophenyl)-1,3-thiazole hydrochloride (CAS: 690632-83-8) is a crystalline solid with a molecular weight of approximately 307.23 g/mol. It is slightly soluble in water and ethanol. The compound is known for its reactivity towards nucleophiles and electrophiles. It displays good thermal stability and is stable in neutral to slightly acidic environments.
How is 4-(Chloromethyl)-2-(3-chlorophenyl)-1,3-thiazole hydrochloride (CAS: 690632-83-8) typically synthesized?
4-(Chloromethyl)-2-(3-chlorophenyl)-1,3-thiazole hydrochloride (CAS: 690632-83-8) is commonly synthesized via a multi-step process involving the reaction of 1-chloro-3-(3-chlorophenyl)thiazol-4(3H)-one with hydrochloric acid. The yield is typically around 70-80%, and the reaction is carried out under mild conditions to ensure high selectivity and purity.
What industries use 4-(Chloromethyl)-2-(3-chlorophenyl)-1,3-thiazole hydrochloride (CAS: 690632-83-8)?
4-(Chloromethyl)-2-(3-chlorophenyl)-1,3-thiazole hydrochloride (CAS: 690632-83-8) is used in the pharmaceutical industry due to its potential as an intermediate in drug synthesis. It is also utilized in the development of sensors and as a component in certain polymer formulations. Its chemical properties make it suitable for a range of applications in these industries.
What precautions should be taken when handling 4-(Chloromethyl)-2-(3-chlorophenyl)-1,3-thiazole hydrochloride (CAS: 690632-83-8)?
When handling 4-(Chloromethyl)-2-(3-chlorophenyl)-1,3-thiazole hydrochloride (CAS: 690632-83-8), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a fume hood to minimize inhalation risks. Spills should be cleaned up using absorbent materials and the area should be well-ventilated. Always refer to the safety data sheet (SDS) for detailed handling and disposal instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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