7-(beta-D-Ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Basic Information

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CAS Number

69-33-0

Molecular Formula

C11H14N4O4

Molecular Weight

266.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

247.8-250 ºC

Boiling Point

409.46°C (rough estimate)

Density

1.90±0.1 g/cm3 (20 ºC 760 Torr),

Refractive Index

1.8340 (estimate)

Specific Rotation

D17 -67° (50% acetic acid)

SMILES

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C1=CN(C2=NC=NC(=C21)N)C3C(C(C(O3)CO)O)O

InChI

InChI=1S/C11H14N4O4/c12-9-5-1-2-15(10(5)14-4-13-9)11-8(18)7(17)6(3-16)19-11/h1-2,4,6-8,11,16-18H,3H2,(H2,12,13,14)/t6-,7-,8-,11-/m1/s1

InChIKey

HDZZVAMISRMYHH-KCGFPETGSA-N

LogP

-1.3750000000000004

Topological Polar Surface Area

126.64999999999999 Å²

Hydrogen Bond Donor/Acceptor

5 / 8

Complexity

334

Safety Information

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GHS Hazard Pictograms

H300

Hazard Statement

H300 Fatal if swallowed
Acute toxicity, oral

Hazard Class

Class 6.1(a) Class 6.1(a)

Toxicity

LD50 i.v. in mice: 45 mg/kg (Anzai)

Synonyms & References

English

BDBM50000298
HY-100126
4-amino-7beta-D-ribofuranosyl-7H-pyrrolo[2, 3-d]pyrimidine
(2R,3R,4S,5R)-2-(4-Amino-pyrrolo[2,3-d]pyrimidin-7-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol
A-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine
7H-Pyrrolo(2,3-d)pyrimidine, 4-amino-7-beta-D-ribofuranosyl-
7-beta-D-Ribofuranosyl-7H-pyrrolo(2,3-d)pyrimidine-4-amine
SCHEMBL8259
U-10071
4-Amino-7-(beta-D-ribofuranosyl)-pyrrolo(2,3-d)pyrimidine
NS00011706
Tubercidin, from Streptomyces tubercidicus, ~95%
Q27089034
7-.BETA.-D-RIBOFURANOSYL-7H-PYRROLO(2,3-D)PYRIMIDIN-4-AMINE
4-26-00-01117 (Beilstein Handbook Reference)
(2R,3R,4S,5R)-2-{4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl}-5-(hydroxymethyl)oxolane-3,4-diol
SMR000471894
69-33-0
7-deaza-adenosine
1pr5
UNII-M351LCX45Y
EINECS 200-703-4
HDZZVAMISRMYHH-KCGFPETGSA-N
EX-A1062
sparsamycin A
(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol
AC-32279
4-Amino-7-(b-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine
(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
cid_6245
SKI 26996

MDL Number

MFCD00056012

Customs Code

29419090

FAQ

What is 7-(beta-D-Ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS: 69-33-0)?

7-(beta-D-Ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a pyrimidine derivative with a ribose sugar moiety. It is an organic compound with a molecular formula of C10H13N5O2. This compound is commonly used in the synthesis of antiviral drugs and as a research tool in molecular biology.

What are the main uses of 7-(beta-D-Ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS: 69-33-0)?

7-(beta-D-Ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is primarily used in the pharmaceutical industry for the development of antiviral drugs. It is also used in research for studying ribonucleoside chemistry and as a building block for nucleoside analogs.

Is 7-(beta-D-Ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS: 69-33-0) safe?

7-(beta-D-Ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is generally considered safe for research and industrial use when handled with appropriate safety precautions. It is essential to follow recommended protective measures, such as the use of gloves and proper ventilation, to minimize exposure to the compound.

How should 7-(beta-D-Ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS: 69-33-0) be stored?

7-(beta-D-Ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine should be stored in a cool, dry place away from heat and direct sunlight. It should be kept in a tightly sealed container to prevent moisture absorption. The storage temperature should be maintained between 15-25°C (59-77°F) to ensure the stability of the compound.