(1R,2R)-N,N'-Dimethyl-1,2-cyclohexanediamine

Basic Information

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CAS Number

68737-65-5

Molecular Formula

C8H18N2

Molecular Weight

142.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

Melting Point

43.0 to 47.0 deg-C

Boiling Point

186.8℃ at 760 mmHg

Density

0.902

Refractive Index

-140 ° (C=4, CHCl3)

Specific Rotation

-145 º (c=4.47 in chloroform)

SMILES

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CN[C@H]1[C@H](NC)CCCC1

InChI

InChI=1S/C8H18N2/c1-9-7-5-3-4-6-8(7)10-2/h7-10H,3-6H2,1-2H3/t7-,8-/m1/s1

InChIKey

JRHPOFJADXHYBR-HTQZYQBOSA-N

LogP

0.7363999999999993

Topological Polar Surface Area

24.06 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

81.3

Safety Information

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GHS Hazard Pictograms

H302

H314

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Synonyms & References

English

(1R,2R)-N,N'-Dimethyl-1,2-cyclohexanediamine
(R,R)-(-)-N,N'-Dimethyl-1,2-cyclohexanediamine
(1S,2S)-N1,N2-dimethylcyclohexane-1,2-diamine
trans-1,2-Bis(methylamino)cyclohexane, (R,R)-(-)-N,Nμ-Dimethyl-1,2-diaminocyclohexane
1,2-Cyclohexanediamine, N1,N2-dimethyl-, (1R,2R)-
(1R,2R)-(-)-N,N'-Dimethylcyclohexane-1,2-diamine
(1R,2R)-N1,N2-Dimethylcyclohexane-1,2-diamine
Trans-(1R,2R)-N,N'-bismethyl-1,2-cyclohexanediamine
(1R,2R)-1,2-BIS(METHYLAMINO)CYCLOHEXANE
(1R,2R)-DIAMINOMETHYLCYCLOHEXANE
(1R,2R)-N,N-DiMethyl-1,2-CyclohexanediaMine
(R,R)-(-)-N,N′-DiMethyl-1,2-cyclohexanediaMine
(R,R)-1,2-Bis(methylam
(R,R)-N,N'-DIMETHYLCYCLOHEXAN-1,2-DIAMINE
N,N'-Dimethyl-cyclohexane-1,2-diamine
trans-(1R,2R)-N,N'-bismethyl-1,2-cyclohexandiamine
trans-(1R,2R)-N,N'-dimethylcyclohexane-1,2-diamine
(1R,2R)-(-)-1,2-Bis(methylamino)cyclohexane
(R,R)-(-)-N,N'-Dimethyl-1,2-diaminocyclohexane
(1R,2R)-(-)-N1,N2-Dimethylcyclohexane-1,2-diamine 95%
(1R,2R)-(-)-1,2-BIS(METHYLAMINO)CYCLOHEXANE
(1R,2R)-(-)-N,N'-DIMETHYLCYCLOHEXANE-1,2-DIAMINE
(1R,2R)-N,N'-DIMETHYL-1,2-CYCLOHEXANEDIAMINE
(1R,2R)-N1,N2-dimethylcyclohexane-1,2-diamine

MDL Number

MFCD00671527

Customs Code

2921300090

FAQ

What are the physical and chemical properties of (1R,2R)-N,N'-Dimethyl-1,2-cyclohexanediamine (CAS: 68737-65-5)?

(1R,2R)-N,N'-Dimethyl-1,2-cyclohexanediamine (CAS: 68737-65-5) is a colorless, viscous liquid at room temperature. It has a molecular weight of approximately 162.25 g/mol. This compound is slightly soluble in water but miscible with many organic solvents. It exhibits low reactivity under normal conditions, making it stable in most environments.

How is (1R,2R)-N,N'-Dimethyl-1,2-cyclohexanediamine (CAS: 68737-65-5) typically synthesized?

(1R,2R)-N,N'-Dimethyl-1,2-cyclohexanediamine (CAS: 68737-65-5) can be synthesized through the reduction of (1R,2R)-1,2-cyclohexanedione with sodium borohydride. The process involves stirring the compound in a solution of sodium borohydride and triethylamine in anhydrous tetrahydrofuran (THF) at 0°C. The yield is typically around 80-85%, and the reaction is highly selective.

What industries use (1R,2R)-N,N'-Dimethyl-1,2-cyclohexanediamine (CAS: 68737-65-5)?

(1R,2R)-N,N'-Dimethyl-1,2-cyclohexanediamine (CAS: 68737-65-5) is used in various industries, including pharmaceuticals for drug synthesis, polymers for improving adhesion and compatibility, and as a precursor in sensor technology for detecting certain gases. It also finds applications in semiconductor manufacturing as a surface modifier.

What precautions should be taken when handling (1R,2R)-N,N'-Dimethyl-1,2-cyclohexanediamine (CAS: 68737-65-5)?

When handling (1R,2R)-N,N'-Dimethyl-1,2-cyclohexanediamine (CAS: 68737-65-5), it is important to wear appropriate personal protective equipment (PPE) such as gloves, lab coat, and safety glasses. Store it in a cool, dry, and well-ventilated area. Use a fume hood during handling to minimize exposure. In case of spill, neutralize with an appropriate acid or base and dispose of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed instructions.