3-Chloro-2-pyrazinamine

Basic Information

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CAS Number

6863-73-6

Molecular Formula

C4H4ClN3

Molecular Weight

129.55 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

166.0 to 170.0 deg-C

Boiling Point

248.1°C at 760 mmHg

Density

1.437

Water Solubility

Slightly soluble in water.

Flash Point

103.8 °C

Refractive Index

1.55

SMILES

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C1=CN=C(C(=N1)N)Cl

InChI

InChI=1S/C4H4ClN3/c5-3-4(6)8-2-1-7-3/h1-2H,(H2,6,8)

InChIKey

AEVSSZHXGJAPIE-UHFFFAOYSA-N

LogP

0.7122

Topological Polar Surface Area

51.8 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

77.7

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

MFCD04114305
3-chloro-pyrazin-2-ylamine
AEVSSZHXGJAPIE-UHFFFAOYSA-N
6663-73-6
Z850999212
3-amino-pyrazinechloride
DTXSID50988309
W-203469
FT-0647238
DICETYLPHOSPHATE,SODIUMSALT
3-amino-2-chloro-pyrazine
3-chloropyrazin-2-amine
Pyrazinamine, 3-chloro-
PS-5664
2-CHLORO-3-AMINEPYRAZINE
AC-3054
FT-0647244
BCP23081
NSC123676
A24738
3-Chloro-2-aminopyrazine
(3-CHLOROPYRAZIN-2-YL)AMINE
AKOS000321645
HY-W007499
SCHEMBL20099
Q-103304
6863-73-6
SY003686
BB 0253839
EN300-60306
CS-W007499

MDL Number

MFCD04114305

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 3-Chloro-2-pyrazinamine (CAS: 6863-73-6)?

3-Chloro-2-pyrazinamine (CAS: 6863-73-6) is a crystalline solid with a molecular weight of approximately 144.57 g/mol. It has a solubility of about 0.2 g/L in water and exhibits basic properties. It is relatively stable under normal conditions but can react with strong acids to form pyrazine derivatives.

How is 3-Chloro-2-pyrazinamine (CAS: 6863-73-6) typically synthesized?

3-Chloro-2-pyrazinamine (CAS: 6863-73-6) can be synthesized via the reaction of 2-chloropyrazine with ammonia. Commonly, this involves the use of a catalyst such as sodium hydroxide to enhance the reaction rate and yield. The process typically yields a product with high purity and selectivity.

What industries use 3-Chloro-2-pyrazinamine (CAS: 6863-73-6)?

3-Chloro-2-pyrazinamine (CAS: 6863-73-6) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of other compounds. It may also find applications in the chemical industry for the production of certain organic compounds and in research for its unique chemical properties.

What precautions should be taken when handling 3-Chloro-2-pyrazinamine (CAS: 6863-73-6)?

Proper handling of 3-Chloro-2-pyrazinamine (CAS: 6863-73-6) requires the use of personal protective equipment (PPE) such as gloves and safety goggles. It should be stored in a well-ventilated area and handled under fume hood conditions to minimize exposure. In the event of a spill, immediate cleanup should be performed following safety protocols and consulting the Material Safety Data Sheet (MSDS) for specific instructions.