1-(2-Methoxyphenyl)methanamine

Basic Information

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CAS Number

6850-57-3

Molecular Formula

C8H11NO

Molecular Weight

137.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Boiling Point

127°C/30mmHg

Density

1.051 g/mL at 25 °C

Refractive Index

n20/D 1.548(lit.)

SMILES

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COC1=CC=CC=C1CN

InChI

InChI=1S/C8H11NO/c1-10-8-5-3-2-4-7(8)6-9/h2-5H,6,9H2,1H3

InChIKey

PXJACNDVRNAFHD-UHFFFAOYSA-N

LogP

1.1539

Topological Polar Surface Area

35.25 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

95.3

Safety Information

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GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Air Sensitive

Synonyms & References

English

(2-Methoxyphenyl)methanamine #
2JK6T542T8
PS-5318
2-METHOXYPHENYLMETHYLAMINE
Benzenemethanamine, 2-methoxy-
2-methoxy-benzyl-amine
M0869
2-methoxybenzyl amine
NS00036617
W-104666
AM20041008
2-methoxy-benzenemethanamine
2-Methoxy-benzyl amine
EN300-18379
InChI=1/C8H11NO/c1-10-8-5-3-2-4-7(8)6-9/h2-5H,6,9H2,1H
MFCD00008110
A836165
CS-W011056
AKOS000120423
BCP11246
(2-methoxyphenyl)-methyl-amine
O-METHOXYBENZENEMETHANAMINE
2-methoxy-benzylamine
V6Q
o-Methoxybenzylamine
DTXSID60218629
FT-0612829
Z57102476
6850-57-3
2-Methoxybenzylamine
2-(Aminomethyl)anisole

MDL Number

MFCD00008110

Customs Code

29221980

FAQ

What are the physical and chemical properties of 1-(2-Methoxyphenyl)methanamine (CAS: 6850-57-3)?

1-(2-Methoxyphenyl)methanamine (CAS: 6850-57-3) is a white or off-white crystalline solid with a molecular weight of approximately 168.21 g/mol. It has a solubility of 2.5 g/L in water and is slightly soluble in ethanol. It is reactive towards bases and oxidizing agents. The compound is stable under normal storage conditions but should be stored in a cool, dry place away from direct sunlight.

How is 1-(2-Methoxyphenyl)methanamine (CAS: 6850-57-3) typically synthesized?

1-(2-Methoxyphenyl)methanamine is typically synthesized through amination of 2-methoxybenzaldehyde with methylamine in the presence of a suitable catalyst such as sodium methoxide. The reaction is carried out in ethanol or another suitable solvent. The product is isolated by recrystallization from an appropriate solvent, and the yield is usually around 80-90%.

What industries use 1-(2-Methoxyphenyl)methanamine (CAS: 6850-57-3)?

1-(2-Methoxyphenyl)methanamine (CAS: 6850-57-3) is used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry as a monomer or intermediate, and in the electronic industry for the production of semiconductors and sensors.

What precautions should be taken when handling 1-(2-Methoxyphenyl)methanamine (CAS: 6850-57-3)?

Proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn when handling 1-(2-Methoxyphenyl)methanamine. The substance should be handled in a well-ventilated area or a fume hood to avoid inhalation of fumes. In case of spill, the area should be flushed with water and the spill cleaned up carefully. Refer to the Safety Data Sheet (SDS) for detailed emergency procedures and storage recommendations.