2-Methyl-2-propanyl (2R)-2-(aminomethyl)-1-piperidinecarboxylate | CAS No. 683233-14-9

2-Methyl-2-propanyl (2R)-2-(aminomethyl)-1-piperidinecarboxylate

Basic Information

CAS Number

683233-14-9

Molecular Formula

C11H22N2O2

Molecular Weight

214.31 g/mol

AD

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Liquid

Density

1.023

CC(C)(C)OC(=O)N1CCCCC1CN

InChI

InChI=1S/C11H22N2O2/c1-11(2,3)15-10(14)13-7-5-4-6-9(13)8-12/h9H,4-8,12H2,1-3H3/t9-/m1/s1

InChIKey

PTVRCUVHYMGECC-SECBINFHSA-N

LogP

1.7347

Topological Polar Surface Area

55.56 Ų

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

223

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • A13069
  • (r)-2-aminomethyl-piperidine-1-carboxylic acid tert-butyl ester
  • 1-Piperidinecarboxylicacid,2-(aminomethyl)-,1,1-dimethylethyl ester,(2R)-
  • EN300-154308
  • SCHEMBL80021
  • (R)-tert-butyl2-(aminomethyl)piperidine-1-carboxylate
  • (R)-tert-butyl 2-(aminomethyl)piperidine-1-carboxylate
  • tert-butyl (2R)-2-(aminomethyl)piperidine-1-carboxylate
  • AKOS005258698
  • tert-butyl (R)-2-(aminomethyl)piperidine-1-carboxylate
  • 1,1-Dimethylethyl (2R)-2-(aminomethyl)-1-piperidinecarboxylate
  • MFCD06659040
  • (r)-2-aminomethyl-n-boc-piperidine
  • (R)-2-(Aminomethyl)-1-N-Boc-piperidine
  • TS-03063
  • 683233-14-9
  • (R)-1-BOC-2-(Aminomethyl)Piperidine
  • 1-piperidinecarboxylic acid, 2-(aminomethyl)-, 1,1-dimethylethyl ester, (2r)-
  • DTXSID80363584
  • (R)-2-Aminomethyl-1-N-Boc-piperidine
  • (r)-tert-butyl-2-(aminomethyl)piperidine-1-carboxylate
  • CS-0002012
  • PTVRCUVHYMGECC-SECBINFHSA-N
  • (R)-2-Aminomethyl-N-Boc-piperidine
  • (R)-2-AMINOMETHYL-1-N-BOC-PIPERIDINE
  • (R)-tert-Butyl 2-(aminomethyl)piperidine-1-carboxylate
  • 1-Piperidinecarboxylic acid, 2-(aminomethyl)-, 1,1-dimethylethyl ester, (2R)-
  • 1,1-dimethylethyl (2R)-2-(aminomethyl)-1-piperidinecarboxylate
  • 1-piperidinecarboxylic acid,2-(aminomethyl)-,1,1-dimethylethyl ester,(2r)
  • (R)-2-(Aminomethyl)-1-N-Boc-piperidine hydrochloride
  • AB25907

MDL Number

MFCD06659040

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl (2R)-2-(aminomethyl)-1-piperidinecarboxylate (CAS: 683233-14-9)?

The compound has a crystalline form at room temperature and a molecular weight of approximately 230.35 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. Chemically, it is reactive towards nucleophiles and can undergo substitution and condensation reactions. The compound is moderately basic due to the piperidine group.

How is 2-Methyl-2-propanyl (2R)-2-(aminomethyl)-1-piperidinecarboxylate (CAS: 683233-14-9) typically synthesized?

This compound is typically synthesized by the condensation of 2-(aminomethyl)-1-piperidinecarboxylic acid with 2-methyl-2-propanol using an acid catalyst such as acetic acid. The reaction proceeds with good selectivity and yields up to 85%.

What industries use 2-Methyl-2-propanyl (2R)-2-(aminomethyl)-1-piperidinecarboxylate (CAS: 683233-14-9)?

This compound is used in pharmaceuticals for its amine functionality, which can be further modified to create active pharmaceutical ingredients. It also has applications in the synthesis of advanced polymers and in the development of sensor technologies. Additionally, it is explored in semiconductor manufacturing for its molecular properties.

What precautions should be taken when handling 2-Methyl-2-proanyl (2R)-2-(aminomethyl)-1-piperidinecarboxylate (CAS: 683233-14-9)?

When handling this compound, wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize exposure. Follow standard safety protocols and have a safety data sheet (SDS) readily available. Spills should be cleaned up with appropriate absorbent materials, and the area should be properly decontaminated. Store it in a cool, dry place away from incompatible materials.

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