2-Bromo-6-chlorothieno[2,3-b]pyridine

Basic Information

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CAS Number

68236-35-1

Molecular Formula

C7H3BrClNS

Molecular Weight

248.53 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

115-116 ºC

Density

1.849±0.06 g/cm3 (20 ºC 760 Torr),

SMILES

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C1=CC(=NC2=C1C=C(S2)Br)Cl

InChI

InChI=1S/C7H3BrClNS/c8-5-3-4-1-2-6(9)10-7(4)11-5/h1-3H

InChIKey

ZXVWVCBUASMPQD-UHFFFAOYSA-N

LogP

3.7122

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

157

Synonyms & References

English

2-bromo-6-chloro-thieno{2,3-b}-pyridine
SCHEMBL7213678
AB48721
CS-0084888
FT-0686048
AMY19056
J-508445
2-bromo-6-chloro-thieno[2,3-b]pyridine
2-BROMO-6-CHLOROTHIENO[2,3-B]PYRIDINE
SY065628
DTXSID30471067
MFCD08706311
68236-35-1
AKOS015950327
P20042
Thieno[2,3-b]pyridine, 2-bromo-6-chloro-
PS-15645
ZXVWVCBUASMPQD-UHFFFAOYSA-N
EN300-261465
2-Bromo-6-chlorothieno[2,3-b]pyridine
2-bromo-6-chlorothieno[2,3-b]pyridine

MDL Number

MFCD08706311

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 2-Bromo-6-chlorothieno[2,3-b]pyridine (CAS: 68236-35-1)?

2-Bromo-6-chlorothieno[2,3-b]pyridine (CAS: 68236-35-1) is a crystalline solid with a molecular weight of approximately 236.01 g/mol. It has low water solubility and is moderately soluble in common organic solvents like DMSO and DMF. This compound exhibits good reactivity towards nucleophiles and electrophiles, making it suitable for various organic synthesis reactions.

How is 2-Bromo-6-chlorothieno[2,3-b]pyridine (CAS: 68236-35-1) typically synthesized?

2-Bromo-6-chlorothieno[2,3-b]pyridine (CAS: 68236-35-1) can be synthesized via a multistep reaction involving bromination and chlorination of thieno[2,3-b]pyridine. The synthesis typically requires careful control of reaction conditions to achieve high yields and selectivity. Commonly used reagents include bromine and chlorine in the presence of appropriate catalysts.

What industries use 2-Bromo-6-chlorothieno[2,3-b]pyridine (CAS: 68236-35-1)?

2-Bromo-6-chlorothieno[2,3-b]pyridine (CAS: 68236-35-1) finds applications in the pharmaceutical industry for its role as a precursor in the synthesis of bioactive compounds. It also has potential uses in the polymer industry for developing novel materials and in the semiconductor industry due to its electronic properties.

What precautions should be taken when handling 2-Bromo-6-chlorothieno[2,3-b]pyridine (CAS: 68236-35-1)?

When handling 2-Bromo-6-chlorothieno[2,3-b]pyridine (CAS: 68236-35-1), appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats should be worn. This compound should be handled in a fume hood to minimize inhalation risks. In case of spills, they should be cleaned up using appropriate absorbents and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.