N-(5-Bromo-2-thienyl)acetamide

Basic Information

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CAS Number

68236-26-0

Molecular Formula

C6H6BrNOS

Molecular Weight

220.09 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

135-136 ºC

Density

1.717±0.06 g/cm3 (20 ºC 760 Torr),

SMILES

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CC(=O)NC1=CC=C(S1)Br

InChI

InChI=1S/C6H6BrNOS/c1-4(9)8-6-3-2-5(7)10-6/h2-3H,1H3,(H,8,9)

InChIKey

SVIZHRDMDNJNMC-UHFFFAOYSA-N

LogP

2.4690000000000003

Topological Polar Surface Area

29.1 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

142

Synonyms & References

English

N-(5-bromothiophen-2-yl)acetamide
SCHEMBL11191679
DTXSID10399871
AKOS016003097
AMY7769
CS-W002831
2-acetamido-5-bromothiophen
N-(2-Bromothiophen-5-yl)acetamide
2-Acetamido-5-bromothiophene
Acetamide,N-(5-bromo-2-thienyl)-
A853064
DS-2317
N-(5-Bromo-2-Thienyl)-Acetamide
SVIZHRDMDNJNMC-UHFFFAOYSA-N
EN300-107212
SY029595
N-(5-bromo-2-thienyl)Acetamide
BCP29992
68236-26-0
FS-3640
FT-0759237
N-(5-bromothiophen-2-yl)acetamide; 2-Acetamido-5-Bromothiophene
MFCD01859880
N-(5-Bromothiophen-2-yl)acetamide
N-(2-BROMOTHIOPHEN-5-YL)-ACETAMIDE
Acetamide,N-(5-bromo-2-thienyl)
N-(5-bromo-thiophen-2-yl)-acetamide
C6H6BrNOS
AB0052846
Z5031
ST24031337

MDL Number

MFCD01859880

Customs Code

2934999090

FAQ

What are the physical and chemical properties of N-(5-Bromo-2-thienyl)acetamide (CAS: 68236-26-0)?

N-(5-Bromo-2-thienyl)acetamide (CAS: 68236-26-0) is a crystalline compound with a molecular weight of approximately 246.03 g/mol. It has a solubility of about 1.2 g/100 mL in water. Chemically, it is less reactive under normal conditions but can undergo nucleophilic substitution reactions. It is slightly soluble in common organic solvents like ethanol and acetone.

How is N-(5-Bromo-2-thienyl)acetamide (CAS: 68236-26-0) typically synthesized?

N-(5-Bromo-2-thienyl)acetamide (CAS: 68236-26-0) is typically synthesized through a multistep process. It involves the bromination of 2-thiophenecarboxaldehyde followed by reaction with acetamide. This process requires careful control of reaction conditions, and the use of anhydrous solvents and appropriate catalysts can enhance yield and selectivity.

What industries use N-(5-Bromo-2-thienyl)acetamide (CAS: 68236-26-0)?

N-(5-Bromo-2-thienyl)acetamide (CAS: 68236-26-0) is primarily used in the pharmaceutical industry for the synthesis of various organosulfur compounds and heterocycles. It also finds applications in polymer chemistry and the development of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling N-(5-Bromo-2-thienyl)acetamide (CAS: 68236-26-0)?

When handling N-(5-Bromo-2-thienyl)acetamide (CAS: 68236-26-0), it is essential to use personal protective equipment (PPE) such as gloves and safety goggles. Store it in a dry and well-ventilated area away from direct sunlight. In case of spillage, use appropriate absorbents and consult the Safety Data Sheet (SDS) for specific cleanup procedures.