2-Methyl-1H-imidazo[4,5-b]pyridine

Basic Information

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CAS Number

68175-07-5

Molecular Formula

C7H7N3

Molecular Weight

133.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

189-190 ºC

Boiling Point

256°C at 760 mmHg

Density

1.31

Flash Point

109 ºC

SMILES

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CC1=NC2=C(N1)C=CC=N2

InChI

InChI=1S/C7H7N3/c1-5-9-6-3-2-4-8-7(6)10-5/h2-4H,1H3,(H,8,9,10)

InChIKey

FZESPVBONPPRAW-UHFFFAOYSA-N

LogP

1.26632

Topological Polar Surface Area

41.57 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

126

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

F19908
DTXSID20902774
SCHEMBL279584
AB26094
DS-13161
MFCD03673741
2-methylimidazopyridine
7239-04-5
2-methyl-1H-imidazo[4,5-b]pyridine
CS-0081070
2-methylimidazo[4,5-b]pyridine
AKOS005174154
FT-0683173
2-Methyl-1H-imidazo[4 pound not5-b]pyridine
SY042119
CCG-321084
Z857667464
SCHEMBL16639356
NoName_3328
68175-07-5
MFCD06659689
AKOS016007606
FZESPVBONPPRAW-UHFFFAOYSA-N
J-509903
EN300-60352
2-Methyl-3H-imidazo[4,5-b]pyridine
2-Methyl-1H-imidazo[4,5-b]pyridine
1H-Imidazo[4,5-b]pyridine, 2-methyl-
2-methyl-3H-imidazo[4,5-b]pyridine
2-Methyl-3H-imidazo[4,5-b]pyridine hydrochloride
2-Methylimidazo[4,5-b]pyridine

MDL Number

MFCD03673741

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2-Methyl-1H-imidazo[4,5-b]pyridine (CAS: 68175-07-5)?

2-Methyl-1H-imidazo[4,5-b]pyridine is a solid with a crystalline form. Its molecular weight is approximately 158.2 g/mol. It has a low solubility in water but is more soluble in organic solvents such as ethanol and acetone. Chemically, it is moderately reactive, particularly towards nucleophiles and electrophiles, and it can undergo substitution reactions.

How is 2-Methyl-1H-imidazo[4,5-b]pyridine (CAS: 68175-07-5) typically synthesized?

2-Methyl-1H-imidazo[4,5-b]pyridine is typically synthesized via a multi-step process involving the condensation of 2-methylpyridine with an imidazole derivative. Commonly, this involves the use of a Lewis acid catalyst and careful control of reaction conditions to achieve good yields and selectivity.

What industries use 2-Methyl-1H-imidazo[4,5-b]pyridine (CAS: 68175-07-5)?

2-Methyl-1H-imidazo[4,5-b]pyridine is primarily used in the pharmaceutical industry for the synthesis of medicinal compounds. It also has applications in the electronic industry for the fabrication of semiconductors and in sensors for its unique reactivity.

What precautions should be taken when handling 2-Methyl-1H-imidazo[4,5-b]pyridine (CAS: 68175-07-5)?

Handling 2-Methyl-1H-imidazo[4,5-b]pyridine requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or a fume hood. Spills should be handled according to the Material Safety Data Sheet (MSDS) guidelines, and the chemical should be stored in a cool, dry place away from sources of ignition.