2-Methyl-1H-imidazo[4,5-b]pyridine(CAS: 68175-07-5)

2-Methyl-1H-imidazo[4,5-b]pyridine is a solid with a crystalline form. Its molecular weight is approximately 158.2 g/mol. It has a low solubility in water but is more soluble in organic solvents such as ethanol and acetone. Chemically, it is moderately reactive, particularly towards nucleophiles and electrophiles, and it can undergo substitution reactions.

2-Methyl-1H-imidazo[4,5-b]pyridine is typically synthesized via a multi-step process involving the condensation of 2-methylpyridine with an imidazole derivative. Commonly, this involves the use of a Lewis acid catalyst and careful control of reaction conditions to achieve good yields and selectivity.

2-Methyl-1H-imidazo[4,5-b]pyridine is primarily used in the pharmaceutical industry for the synthesis of medicinal compounds. It also has applications in the electronic industry for the fabrication of semiconductors and in sensors for its unique reactivity.

Handling 2-Methyl-1H-imidazo[4,5-b]pyridine requires the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be handled in a well-ventilated area or a fume hood. Spills should be handled according to the Material Safety Data Sheet (MSDS) guidelines, and the chemical should be stored in a cool, dry place away from sources of ignition.