4'-[2-(DIMETHYLAMINO)ETHOXY]-2-PHENYLBUTYROPHENONE | CAS No. 68047-07-4

4'-[2-(DIMETHYLAMINO)ETHOXY]-2-PHENYLBUTYROPHENONE

Basic Information

CAS Number

68047-07-4

Molecular Formula

C20H25NO2

Molecular Weight

311.42 g/mol

AD

Basic Physical Properties

Density

1.051±0.06 g/cm3 (20 ºC 760 Torr),

CCC(C1=CC=CC=C1)C(=O)C2=CC=C(C=C2)OCCN(C)C

InChI

InChI=1S/C20H25NO2/c1-4-19(16-8-6-5-7-9-16)20(22)17-10-12-18(13-11-17)23-15-14-21(2)3/h5-13,19H,4,14-15H2,1-3H3

InChIKey

OBBFYFBJWYPOQQ-UHFFFAOYSA-N

LogP

4.003500000000003

Topological Polar Surface Area

29.54 Ų

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

342

Synonyms & References

English

  • 1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbutan-1-one
  • DTXSID30987496
  • 4-(beta-dimethylaminoethoxy)-alpha-ethyldesoxybenzoin
  • 1-{4-[2-(dimethylamino)ethoxy]phenyl}-2-phenyl-1-butanone
  • 4'-[2-(DIMETHYLAMINO)ETHOXY]-2-PHENYLBUTYROPHENONE
  • 1-(4-(2-(Dimethylamino)ethoxy)phenyl)-2-phenylbutan-1-one
  • 1-Butanone, 1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenyl-
  • UNII-47BUC43043
  • TAMOXIFEN CITRATE IMPURITY G [EP IMPURITY]
  • Tamoxifen Citrate Imp. G (EP); Tamoxifen Imp. G (EP); (2RS)-1-[4-[2-(Dimethylamino)-ethoxy]phenyl]-2-phenylbutan-1-one; Tamoxifen Citrate Impurity G; Tamoxifen Impurity G
  • (2RS)-1-(4-(2-(Dimethylamino)ethoxy)phenyl)-2-phenylbutan-1-one
  • 47BUC43043
  • OBBFYFBJWYPOQQ-UHFFFAOYSA-N
  • Tamoxifen citrate impurity G [EP]
  • SCHEMBL2058475
  • 1-(4-(2-(Dimethylamino)ethoxy)phenyl)-2-phenylbutan-1-one, (2RS)-
  • CHEMBL4636026
  • 1-{4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL}-2-PHENYLBUTAN-1-ONE
  • 1-[4-(2-dimethylaminoethoxy)phenyl]-2-phenyl-1-butanone
  • 1-Butanone, 1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-
  • 68047-07-4
  • Q27259042
  • 1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenyl-1-butanone
  • 1-(4-(2-Dimethylamino)-2-ethoxyphenyl butanone
  • 1-p-dimethylaminoethoxyphenyl-2-phenyl-butan-1-one

MDL Number

MFCD12973614

FAQ

What are the physical and chemical properties of 4'-[2-(DIMETHYLAMINO)ETHOXY]-2-PHENYLBUTYROPHENONE (CAS: 68047-07-4)?

4'-[2-(DIMETHYLAMINO)ETHOXY]-2-PHENYLBUTYROPHENONE is a white crystalline solid with a molecular weight of approximately 325.45 g/mol. It is slightly soluble in water and more soluble in organic solvents like dimethylformamide and dimethyl sulfoxide. It is moderately reactive, particularly under basic conditions. This compound is stable under normal laboratory conditions but should be stored in a cool, dry place away from direct sunlight.

How is 4'-[2-(DIMETHYLAMINO)ETHOXY]-2-PHENYLBUTYROPHENONE (CAS: 68047-07-4) typically synthesized?

4'-[2-(DIMETHYLAMINO)ETHOXY]-2-PHENYLBUTYROPHENONE is synthesized through a multi-step reaction. The key steps involve the introduction of a dimethylamino ethoxy group via a nucleophilic substitution reaction. Commonly, this involves using ethoxy(dimethylamino)methyl ether in the presence of a base like sodium hydride. The reaction is typically carried out in anhydrous conditions to improve yield and selectivity.

What industries use 4'-[2-(DIMETHYLAMINO)ETHOXY]-2-PHENYLBUTYROPHENONE (CAS: 68047-07-4)?

4'-[2-(DIMETHYLAMINO)ETHOXY]-2-PHENYLBUTYROPHENONE is primarily used in the pharmaceutical industry for its potential as an intermediate in the synthesis of other compounds. It is also explored in the semiconductor industry for its use in organic electronic devices and in the development of new materials for sensors. However, its specific applications may vary depending on the industry and the research focus.

What precautions should be taken when handling 4'-[2-(DIMETHYLAMINO)ETHOXY]-2-PHENYLBUTYROPHENONE (CAS: 68047-07-4)?

When handling 4'-[2-(DIMETHYLAMINO)ETHOXY]-2-PHENYLBUTYROPHENONE, it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be thoroughly washed down. Always refer to a Material Safety Data Sheet (MSDS) for specific handling and storage guidelines.

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