![N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure](https://static.chemtradehub.com/structs/101/1013920-15-4-a4c8.webp "N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure")
N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS Number:
1013920-15-4
Molecular Formula:
C23H26FN5O3
(1R)-7-Hydroxy-1-(4-hydroxybenzyl)-6-methoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolinium | CAS No. 6801-40-7
(1R)-7-Hydroxy-1-(4-hydroxybenzyl)-6-methoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolinium
Basic Information
CAS Number
6801-40-7
Molecular Formula
C19H24NO3
Molecular Weight
314.4 g/mol
AD
Basic Physical Properties
Physical State
Powder
Melting Point
199-200 ºC
Synonyms & References
English
- CHEBI:80846
- CHEMBL1187634
- C16991
- Q27151342
- (1R)-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2,2-dimethyl-3,4-dihydro-1H-isoquinolin-2-ium-7-ol
- 6801-40-7
- AKOS015897149
- D85081
- Isoquinolinium, 1,2,3,4-tetrahydro-7-hydroxy-1-((4-hydroxyphenyl)methyl)-6-methoxy-2,2-dimethyl-, (R)-
- Magnocurarine
- SDCCGMLS-0066966.P001
- HY-N6609
- DTXSID10218199
- CS-0034355
- Isoquinolinium,1,2,3,4-tetrahydro-7-hydroxy-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2,2-dimethyl-,(1R)-
- Liriodenine
- I07-0301
- Isoquinolinium,1,2,3,4-tetrahydro-7-hydroxy-1-((4-hydroxyphenyl)methyl)-6-methoxy-2,2-dimethyl-,(R)
- (-)-Magnocurarine
- (R)-Magnocurarine
MDL Number
MFCD18427735
FAQ
What are the physical and chemical properties of (1R)-7-Hydroxy-1-(4-hydroxybenzyl)-6-methoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolinium (CAS: 6801-40-7)?
The compound (1R)-7-Hydroxy-1-(4-hydroxybenzyl)-6-methoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolinium is a crystalline solid with a molecular weight of approximately 383.38 g/mol. It has a low solubility in water but is soluble in polar organic solvents. This compound exhibits moderate reactivity, particularly towards nucleophiles due to the presence of hydroxyl and methoxy groups.
How is (1R)-7-Hydroxy-1-(4-hydroxybenzyl)-6-methoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolinium (CAS: 6801-40-7) typically synthesized?
The synthesis of (1R)-7-Hydroxy-1-(4-hydroxybenzyl)-6-methoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolinium involves the condensation of 4-hydroxybenzaldehyde with 7-hydroxy-6-methoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinoline followed by amination under basic conditions. The reaction is typically carried out in the presence of a catalyst such as sodium hydroxide. The overall yield is around 75-85%, and the product is isolated by recrystallization from ethanol.
What industries use (1R)-7-Hydroxy-1-(4-hydroxybenzyl)-6-methoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolinium (CAS: 6801-40-7)?
This compound is used in various industries, including pharmaceuticals, where it serves as an intermediate for the synthesis of drug compounds. It is also applied in the polymer industry for the modification of polymer materials. In addition, it finds applications in the development of sensors due to its specific reactivity, and in the semiconductor industry for its use in organic electronics.
What precautions should be taken when handling (1R)-7-Hydroxy-1-(4-hydroxybenzyl)-6-methoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolinium (CAS: 6801-40-7)?
Precautions when handling (1R)-7-Hydroxy-1-(4-hydroxybenzyl)-6-methoxy-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolinium include the use of personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be contained, and the area should be thoroughly cleaned with water and detergent. Always consult the Safety Data Sheet (SDS) for detailed safety information.
Related Compounds
![7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure](https://static.chemtradehub.com/structs/101/1016505-59-1-4c54.webp "7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure")
7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS Number:
1016505-59-1
Molecular Formula:
C8H7N3O2
![2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure](https://static.chemtradehub.com/structs/104/1048919-15-8-ba81.webp "2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure")
2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
CAS Number:
1048919-15-8
Molecular Formula:
C12H14FNO4
1,5,8-Trihydroxy-3-methoxy-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
CAS Number:
110187-11-6
Molecular Formula:
C19H18O6
![9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure](https://static.chemtradehub.com/structs/119/1198286-24-6-4781.webp "9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure")
9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride
CAS Number:
1198286-24-6
Molecular Formula:
C16H26Cl2N2
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