2-Methoxy-5-nitroaniline hydrochloride (1:1)

Basic Information

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CAS Number

67827-72-9

Molecular Formula

C7H9ClN2O3

Molecular Weight

204.61 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

118 deg C

Boiling Point

351.8 °C at 760 mmHg

Flash Point

351.8 °C at 760 mmHg

SMILES

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COC1=C(C=C(C=C1)[N+](=O)[O-])N.Cl

InChI

InChI=1S/C7H8N2O3.ClH/c1-12-7-3-2-5(9(10)11)4-6(7)8;/h2-4H,8H2,1H3;1H

InChIKey

JBBNYKPRONOPHN-UHFFFAOYSA-N

LogP

3.09200

Complexity

169

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

A835898
2-Methoxy-5-nitroaniline, monohydrochloride
FT-0694528
EINECS 267-234-5
o-Anisidine, 5-nitro-, hydrochloride
SCHEMBL21772081
2-Methoxy-5-Nitro Aniline HCl
67827-72-9
4DP906MMG9
2-Methoxy-5-nitroanilinium chloride
Benzenamine, 2-methoxy-5-nitro-, hydrochloride (1:1)
O10818
EN300-35941
CS-0247190
2-methoxy-5-nitroaniline hydrochloride
NIOSH/BZ7177000
Benzenamine, 2-methoxy-5-nitro-, monohydrochloride
BZ71770000
2-Methoxy-5-nitroaniline HCl
Q27259459
DS-3377
2-Methoxy-5-nitroaniline Monohydrochloride
2-amino-4-nitroanisole hydrochloride
AMY40950
W-104701
4-Nitro-2-aminoanisole hydrochloride
UNII-4DP906MMG9
2-methoxy-5-nitroaniline;hydrochloride
5-Nitro-o-anisidine hydrochloride
MFCD00060197
AC-2666

MDL Number

MFCD04110822

Customs Code

2922299090

FAQ

What are the physical and chemical properties of 2-Methoxy-5-nitroaniline hydrochloride (CAS: 67827-72-9)?

2-Methoxy-5-nitroaniline hydrochloride (CAS: 67827-72-9) is a crystalline solid with a molecular weight of approximately 217.04 g/mol. It has a pKa of 1.5 and is highly soluble in water, with a solubility of 12.8 g/100 mL at 20°C. The compound is moderately reactive, especially towards reducing agents and bases. It exhibits good solubility in common organic solvents like methanol and ethanol.

How is 2-Methoxy-5-nitroaniline hydrochloride (CAS: 67827-72-9) typically synthesized?

2-Methoxy-5-nitroaniline hydrochloride is typically synthesized by the reaction of 2-methoxy-5-nitroaniline with hydrochloric acid. The process involves dissolving the aniline in hydrochloric acid, followed by recrystallization from an appropriate solvent to obtain the hydrochloride salt. The reaction is carried out under mild conditions, and the yield is generally around 85-90%.

What industries use 2-Methoxy-5-nitroaniline hydrochloride (CAS: 67827-72-9)?

2-Methoxy-5-nitroaniline hydrochloride (CAS: 67827-72-9) is primarily used in pharmaceuticals and dyes. It serves as a precursor for the synthesis of various pharmaceutical compounds and also as a coloring agent in textile dyes. Additionally, it finds applications in the production of some organic pigments and as a reagent in analytical chemistry.

What precautions should be taken when handling 2-Methoxy-5-nitroaniline hydrochloride (CAS: 67827-72-9)?

When handling 2-Methoxy-5-nitroaniline hydrochloride (CAS: 67827-72-9), it is essential to use personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be carried out in a well-ventilated area or a fume hood to minimize exposure to vapors. Spills should be cleaned up using absorbent materials and disposed of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed emergency procedures and safe handling instructions.