6-Fluoronicotinaldehyde

Basic Information

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CAS Number

677728-92-6

Molecular Formula

C6H4FNO

Molecular Weight

125.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

228.9℃ at 760 mmHg

SMILES

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C1=CC(=NC=C1C=O)F

InChI

InChI=1S/C6H4FNO/c7-6-2-1-5(4-9)3-8-6/h1-4H

InChIKey

PZPNGWWKCSJKOS-UHFFFAOYSA-N

LogP

1.0332000000000001

Topological Polar Surface Area

29.96 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

107

Safety Information

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Hazard Statement

Hazard Class

Class 3 Class 3

Synonyms & References

English

6-fluoranylpyridine-3-carbaldehyde
6-Fluoronicotinaldehyde
677728-92-6
6-fluoropyridine-3-carbaldehyde
PS-9205
PZPNGWWKCSJKOS-UHFFFAOYSA-N
SY022307
2-fluoro-5-formyl pyridine
AC-1873
BDBM92854
CS-W004680
SCHEMBL114830
FT-0645268
AMY7971
PB23560
Nicotinamidase Inhibitor, 21
A835884
3-PYRIDINECARBOXALDEHYDE, 6-FLUORO-
AKOS006344489
6-fluoro-3-pyridinecarboxaldehyde
6-fluoro-3-pyridine carboxaldehyde
MFCD08064049
2-FLUORO-5-FORMYLPYRIDINE
DTXSID80585986
6-fluoro-pyridine-3-carbaldehyde
J-518755
EN300-112291
2-FLUORO-5-PYRIDINECARBOXALDEHYDE
2-Fluoropyridine-5-carboxaldehyde
A9070
2-Fluoropyridine-5-carbaldehyde

MDL Number

MFCD08064049

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 6-Fluoronicotinaldehyde (CAS: 677728-92-6)?

6-Fluoronicotinaldehyde is a colorless to light yellow liquid with a vapor pressure of 1.2 mm Hg at 25°C. It has a molecular weight of 148.06 g/mol and a solubility in water of 1.45 g/L. This compound is reactive and prone to hydrolysis and reduction under certain conditions.

How is 6-Fluoronicotinaldehyde (CAS: 677728-92-6) typically synthesized?

6-Fluoronicotinaldehyde is typically synthesized through the reaction of 6-fluoronicotinic acid with formaldehyde in the presence of an acid catalyst such as sulfuric acid. The reaction involves the condensation of the acid with formaldehyde followed by dehydration to form the aldehyde.

What industries use 6-Fluoronicotinaldehyde (CAS: 677728-92-6)?

6-Fluoronicotinaldehyde is used in the pharmaceutical industry for the synthesis of drug intermediates, particularly in the development of anti-inflammatory and anticancer drugs. It is also utilized in the polymer industry for the production of certain polymers, and in the sensor industry for the development of gas sensors.

What precautions should be taken when handling 6-Fluoronicotinaldehyde (CAS: 677728-92-6)?

When handling 6-Fluoronicotinaldehyde, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a fume hood to minimize exposure to vapors. Spills should be handled with caution, and proper spill cleanup procedures should be followed. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.