(1R,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine

Basic Information

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CAS Number

675126-05-3

Molecular Formula

C16H15Cl2N

Molecular Weight

292.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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C1CC(C2=CC=CC=C2C1C3=CC(=C(C=C3)Cl)Cl)N

InChI

InChI=1S/C16H15Cl2N/c17-14-7-5-10(9-15(14)18)11-6-8-16(19)13-4-2-1-3-12(11)13/h1-5,7,9,11,16H,6,8,19H2/t11-,16+/m0/s1

InChIKey

SRPXSILJHWNFMK-MEDUHNTESA-N

LogP

4.9189000000000025

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

309

Synonyms & References

English

NS00069019
SEP-225,289
Dasotraline [USAN:INN]
(1r,4s)-4-(3,4-dichloro-phenyl)-1,2,3,4-tetrahydro-naphthalen-1-ylamine
(1R,4S)-trans-Norsertraline
CHEMBL3301595
Q27076989
1-NAPHTHALENAMINE, 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-, (1R,4S)-
Dasotraline
CS-0012724
A857937
(1R,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-amine
Norsertraline, (1R,4S)-trans-
DTXSID20217855
UNII-4D28EY0L5T
GTPL8308
SCHEMBL263142
EX-A2622
Dasotraline (USAN/INN)
D10700
DASOTRALINE [USAN]
Dasotraline; SEP 225289
HY-12850
BCP24754
DASOTRALINE [WHO-DD]
DASOTRALINE [INN]
4D28EY0L5T
DB12305
SEP-225289
Dasotraline(SEP-225289) free base
675126-05-3

MDL Number

MFCD07772551

FAQ

What are the physical and chemical properties of (1R,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine (CAS: 675126-05-3)?

The compound (1R,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine has a crystalline form with a molecular weight of approximately 300 g/mol. It is slightly soluble in water but more soluble in organic solvents like methanol and ethanol. The compound is chemically stable under normal conditions but can react with strong oxidizing agents. It also exhibits limited reactivity with bases and acids.

How is (1R,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine (CAS: 675126-05-3) typically synthesized?

(1R,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine is typically synthesized through a multistep process involving the reaction of 3,4-dichlorobenzaldehyde with 1-naphthylamine. The synthesis involves the use of a Lewis acid catalyst, such as aluminum chloride, and proceeds with good yield. The product is then purified by recrystallization from a suitable solvent.

What industries use (1R,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine (CAS: 675126-05-3)?

(1R,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine is primarily used in the pharmaceutical industry for the development of certain drugs. It also has applications in the polymer industry, where it can be used as a modifier or stabilizer. Additionally, it has some use in the sensor and semiconductor industries as a precursor or dopant material.

What precautions should be taken when handling (1R,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine (CAS: 675126-05-3)?

When handling (1R,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize exposure. In the event of a spill, it should be cleaned up using absorbent materials and disposed of according to local regulations. Always refer to the safety data sheet (SDS) for detailed handling instructions and safety information.

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(1R,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine | CAS No. 675126-05-3

Basic Information

CAS Number

Molecular Formula

Molecular Weight

Chemical Classification

Basic Physical Properties

Chemical Properties

SMILES

InChI

InChIKey

LogP

Topological Polar Surface Area

Hydrogen Bond Donor/Acceptor

Complexity

Synonyms & References

English

MDL Number

FAQ

What are the physical and chemical properties of (1R,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine (CAS: 675126-05-3)?

How is (1R,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine (CAS: 675126-05-3) typically synthesized?

What industries use (1R,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine (CAS: 675126-05-3)?

What precautions should be taken when handling (1R,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine (CAS: 675126-05-3)?

Related Compounds

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Supplier Information

ShenZhenAiTaHuaXue Co Ltd

Jin Jinle (Hunan) Chemical Co., Ltd.

Shanghai Jieshukai Biotechnology Co., Ltd.

Shanghai Hansi Chemical Co., Ltd.

ShangHaiChuangSai Technology Co Ltd

ShangHaiZhenZhun Biotechnology Co Ltd

Shanghai Yuyeh Biotechnology Co., Ltd.

Shanghai Guanyin Biotechnology Co., Ltd.

Shanghai Yuansi Biotechnology Co., Ltd.

Hubei Hanwei Chemical Co., Ltd.

ShangHaiPoFaMuYiYao Technology Co Ltd

Wuhu Linze Pharmaceutical Technology Co., Ltd.

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