(R,R)-Formoterol (Arformoterol)

Basic Information

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CAS Number

67346-49-0

Molecular Formula

C19H24N2O4

Molecular Weight

344.41 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Boiling Point

603.2°C at 760 mmHg

SMILES

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COc1ccc(C[C@@H](C)NC[C@H](O)c2ccc(O)c(NC=O)c2)cc1

InChI

InChI=1S/C19H24N2O4/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22)/t13-,19+/m1/s1

InChIKey

BPZSYCZIITTYBL-YJYMSZOUSA-N

LogP

2.2233

Topological Polar Surface Area

90.82 Å²

Hydrogen Bond Donor/Acceptor

4 / 6

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Arformoterol base
(R,R)-Formoterol
Arformoterol
Formamide, N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1-methylethyl]amino]ethyl]phenyl]-, (2R,3R)-
(-)-Formoterol
N-[2-Hydroxy-5-[1(R)-hydroxy-2-[2-(4-methoxyphenyl)-1(R)-methylethylamino]ethyl]phenyl]formamide
N-(2-hydroxy-5-((R)-1-hydroxy-2-(((R)-1-(4-methoxyphenyl)propan-2-yl)amino)ethyl)phenyl)formamide

MDL Number

MFCD00864141

FAQ

What is (R,R)-Formoterol (CAS: 67346-49-0)?

(R,R)-Formoterol, also known as Arformoterol, is a selective β2-adrenergic receptor agonist. It is used as a bronchodilator in the treatment of asthma and chronic obstructive pulmonary disease (COPD). Its chemical formula is C16H18N2O3. It is a white to off-white crystalline powder with a bitter taste.

What are the main uses of (R,R)-Formoterol (CAS: 67346-49-0)?

(R,R)-Formoterol (CAS: 67346-49-0) is primarily used as a bronchodilator in the management of asthma and chronic obstructive pulmonary disease (COPD). It is administered via inhalation to provide long-lasting relief and improve lung function. It is also used in combination with corticosteroids for better control of respiratory symptoms.

Is (R,R)-Formoterol (CAS: 67346-49-0) safe?

(R,R)-Formoterol (CAS: 67346-49-0) is generally considered safe when used as directed. However, it can cause side effects such as tremors, headache, and palpitations. It is important to follow medical advice and not exceed the prescribed dose. Users should be monitored for signs of cardiovascular effects, especially in patients with underlying heart conditions.

How should (R,R)-Formoterol (CAS: 67346-49-0) be stored?

(R,R)-Formoterol (CAS: 67346-49-0) should be stored at 15°C to 30°C (59°F to 86°F) in a tightly closed container. Keep it away from direct sunlight, moisture, and heat. Store it out of reach of children and pets. It should be protected from freezing and should not be exposed to temperatures below 0°C (32°F).