O-(oxan-2-yl)hydroxylamine

Basic Information

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CAS Number

6723-30-4

Molecular Formula

C5H11NO2

Molecular Weight

117.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

34-37 °C

Boiling Point

81 °C/20 mmHg

Density

1.1274 (rough estimate)

Refractive Index

1.4206 (estimate)

SMILES

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C1CCOC(C1)ON

InChI

InChI=1S/C5H11NO2/c6-8-5-3-1-2-4-7-5/h5H,1-4,6H2

InChIKey

NLXXVSKHVGDQAT-UHFFFAOYSA-N

LogP

0.40329999999999977

Topological Polar Surface Area

44.480000000000004 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

67.4

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

O-(Tetrahydropyran-2-yl)-hydroxylamine
O-(oxan-2-yl)hydroxylamine
Z968560364
O-tetrahydro-2H-pyran-2yl-hydroxylamine
MFCD01321374
CHEMBL1213808
SCHEMBL42789
NH2OTHP
GS-3273
O-tetrahydro-2H-pyran-2-ylhydroxylamine
N-(2-tetrahydropyranyloxy)amine
O-(2-tetrahydropyranyl)-hydroxylamine
O-(tetrahydro-2H-pyran-yl)hydroxylamine
o-(tetrahydro-2h-pyran-2(rs)-yl)hydroxylamine
DTXSID50408719
H2N-OTHP
O-(TERTRAHYDROXY-PYRAN-2-YL)-HYDROXYLAMINE
Hydroxylamine, O-(tetrahydro-2H-pyran-2-yl)-
O-(Tetrahydropyran-2-yl)-Hydroxylamne
NLXXVSKHVGDQAT-UHFFFAOYSA-N
O-(Tetrahydro-pyran-2-yl)-hydroxylamine
EN300-61519
2-(aminooxy)tetrahydro-2H-pyrane
O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine, 96%
O-(Tetrahydro-pyran-2-yl)hydroxylamine
O-tetrahydropyranyl hydroxylamine
H2NOTHP
O-tetrahydropyran-2-ylhydroxylamine
O-(tetrahydro-2H-pyran-2-yl)-hydroxylamine
2-tetrahydropyranyloxyamine
O-tetrahydropyranylhydroxylamine

MDL Number

MFCD01321374

Customs Code

2932999099

FAQ

What are the physical and chemical properties of O-(oxan-2-yl)hydroxylamine (CAS: 6723-30-4)?

O-(oxan-2-yl)hydroxylamine is a white crystalline solid with a molecular weight of approximately 118.14 g/mol. It is slightly soluble in water and more soluble in organic solvents such as ethanol and acetone. It is a reducing agent and can react with various oxidizing agents. This compound has a pKa of approximately 10.8, indicating basic properties.

How is O-(oxan-2-yl)hydroxylamine (CAS: 6723-30-4) typically synthesized?

O-(oxan-2-yl)hydroxylamine is typically synthesized via the reduction of oxan-2-yl nitrile with a reducing agent like sodium borohydride. The reaction is carried out in a suitable solvent such as methanol or ethanol. The yield of the product can be up to 80-90%, depending on the purity of the starting material and the reaction conditions.

What industries use O-(oxan-2-yl)hydroxylamine (CAS: 6723-30-4)?

O-(oxan-2-yl)hydroxylamine is used in the pharmaceutical industry for the synthesis of certain drugs. It is also employed in the polymer industry for the modification of polymers and in the sensor industry for the development of gas sensors. Additionally, it can be used in the semiconductor industry as a chemical reagent.

What precautions should be taken when handling O-(oxan-2-yl)hydroxylamine (CAS: 6723-30-4)?

When handling O-(oxan-2-yl)hydroxylamine, it is important to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. This compound should be handled in a well-ventilated area or fume hood to avoid inhalation of vapors. Spills should be handled with caution, using an appropriate absorbent material, and the area should be flushed with water. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.