2-(trifluoromethyl)pyrimidin-4-amine

Basic Information

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CAS Number

672-42-4

Molecular Formula

C5H4F3N3

Molecular Weight

163.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

155.3℃/760mmHg

Density

1.46

Flash Point

47.7°C

Refractive Index

1.478

SMILES

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C1=CN=C(N=C1N)C(F)(F)F

InChI

InChI=1S/C5H4F3N3/c6-5(7,8)4-10-2-1-3(9)11-4/h1-2H,(H2,9,10,11)

InChIKey

XJHPDOAHPIXTPH-UHFFFAOYSA-N

LogP

1.0776000000000001

Topological Polar Surface Area

51.8 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

135

Synonyms & References

English

SCHEMBL1420222
DS-4997
MFCD08436606
SY065353
J-510352
2-(trifluoromethyl)pyrimidin-4-amine
672-42-4
2-Trifluoromethyl-pyrimidin-4-ylamine
F2124-0828
SB57437
CS-0045047
2-Trifluoromethylpyrimidin-4-ylamine
NSC-54425
2-TRIFLUOROMETHYL-4-AMINOPYRIMIDINE
DTXSID30288172
FT-0687938
4-Amino-2-(trifluoromethyl)pyrimidine
EN300-238183
NSC54425
XJHPDOAHPIXTPH-UHFFFAOYSA-N
BB 0262526
AKOS000320550
2-(trifluoromethyl)-4-Pyrimidinamine
BCP04494
2-(Trifluoromethyl)pyrimidin-4-amine
2-(Trifluoromethyl)-4-pyrimidinamine
HP21629
RP22582
AK135429
AB0096240
Z2614

MDL Number

MFCD08436606

FAQ

What regulatory guidelines apply to 2-(trifluoromethyl)pyrimidin-4-amine (CAS: 672-42-4)?

2-(Trifluoromethyl)pyrimidin-4-amine (CAS: 672-42-4) should comply with various regulatory guidelines, including GHS classification for hazardous substances, REACH regulations for European market, and FDA and EPA requirements for pharmaceutical and environmental concerns. Specific handling, storage, and disposal methods should be in accordance with local and international laws.

Are there alternatives to 2-(trifluoromethyl)pyrimidin-4-amine (CAS: 672-42-4) in synthesis?

In synthesis, 2-(trifluoromethyl)pyrimidin-4-amine (CAS: 672-42-4) can be replaced by similar compounds like 2-(trifluoromethyl)pyrimidin-5-amine or related 2-(heteroaryl)pyrimidinamines. These alternatives offer similar functional groups for chemical transformations, but the choice depends on specific reaction conditions and desired product properties.

What is the market or research trend for 2-(trifluoromethyl)pyrimidin-4-amine (CAS: 672-42-4)?

The market and research trends for 2-(trifluoromethyl)pyrimidin-4-amine (CAS: 672-42-4) are predominantly focused on its use in pharmaceuticals and agrochemicals due to its biological activity. Recent studies are exploring its potential as an anti-inflammatory and antiviral agent. Additionally, there is growing interest in developing new synthetic routes and improving the environmental impact of its production and use.

How should waste containing 2-(trifluoromethyl)pyrimidin-4-amine (CAS: 672-42-4) be handled?

Waste containing 2-(trifluoromethyl)pyrimidin-4-amine (CAS: 672-42-4) should be collected in appropriate containers, ensuring it is labeled with hazardous waste indicators. Proper waste disposal methods include incineration under controlled conditions or professional waste disposal services that comply with environmental regulations. Protective measures should be taken to prevent environmental contamination and ensure safe handling and transport of waste materials.