2-Amino-5-methoxybenzoic acid

Basic Information

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CAS Number

6705-03-9

Molecular Formula

C8H9NO3

Molecular Weight

167.16 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

Melting Point

148-152 °C

Boiling Point

349.9±27.0 °C at 760 mmHg

Density

1.303

Flash Point

165.4℃

Refractive Index

1.603

SMILES

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COC1=CC(=C(C=C1)N)C(=O)O

InChI

InChI=1S/C8H9NO3/c1-12-5-2-3-7(9)6(4-5)8(10)11/h2-4H,9H2,1H3,(H,10,11)

InChIKey

UMKSAURFQFUULT-UHFFFAOYSA-N

LogP

0.9756

Topological Polar Surface Area

72.55 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

172

Safety Information

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GHS Hazard Pictograms

H302

H319

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

DTXSID50298930
AKOS005145853
BCP10331
CHEBI:181435
6705-03-9
Z594219052
5-Methoxyanthranilic acid
NICLOSAMIDEPIPERAZINESALT
EN300-105839
NSC-126996
2-amino-5-methoxy benzoic acid
MFCD00016509
SCHEMBL221141
FT-0636243
2-Amino-5-methoxybenzoic acid
5-methoxy anthranilic acid
NSC126996
SY014917
AN-584/43074539
2-Amino-5-methoxybenzoic acid, 97%
2-amino-5-methoxy-benzoic acid
2-Amino-5-methoxybenzoic acid #
AM20060709
PS-6044
Benzoic acid, 2-amino-5-methoxy-
2-Amino-5-methoxybenzoicacid
CS-W009211
3-Methoxy-6-aminobenzoic acid
AC-1669
2-Amino-5-methoxy-benzoic acid
2-amino-5-methoxybenzoesyre

MDL Number

MFCD00016509

Customs Code

2942000000

FAQ

What are the physical and chemical properties of 2-Amino-5-methoxybenzoic acid (CAS: 6705-03-9)?

2-Amino-5-methoxybenzoic acid is a solid with a crystalline form. Its molecular weight is approximately 191.16 g/mol. It is slightly soluble in water and ethanol. Chemically, it is less reactive than many carboxylic acids but can undergo esterification and other reactions. It has a pKa of about 4.5.

How is 2-Amino-5-methoxybenzoic acid (CAS: 6705-03-9) typically synthesized?

2-Amino-5-methoxybenzoic acid can be synthesized via the methylation of 5-hydroxybenzoic acid followed by the coupling with an amine. Commonly, this involves the use of methyl iodide and sodium hydride as a catalyst, with a yield of around 70-80%.

What industries use 2-Amino-5-methoxybenzoic acid (CAS: 6705-03-9)?

2-Amino-5-methoxybenzoic acid is used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the production of sensors and as a precursor in the polymer industry for improving the properties of plastics and resins.

What precautions should be taken when handling 2-Amino-5-methoxybenzoic acid (CAS: 6705-03-9)?

When handling 2-Amino-5-methoxybenzoic acid, it is important to use appropriate personal protective equipment (PPE) such as gloves and goggles. It should be stored in a cool, dry place away from direct sunlight. In case of spill, avoid inhalation and contact with eyes or skin. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.