2-Amino-5-methoxybenzoic acid(CAS: 6705-03-9)

2-Amino-5-methoxybenzoic acid is a solid with a crystalline form. Its molecular weight is approximately 191.16 g/mol. It is slightly soluble in water and ethanol. Chemically, it is less reactive than many carboxylic acids but can undergo esterification and other reactions. It has a pKa of about 4.5.

2-Amino-5-methoxybenzoic acid can be synthesized via the methylation of 5-hydroxybenzoic acid followed by the coupling with an amine. Commonly, this involves the use of methyl iodide and sodium hydride as a catalyst, with a yield of around 70-80%.

2-Amino-5-methoxybenzoic acid is used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the production of sensors and as a precursor in the polymer industry for improving the properties of plastics and resins.

When handling 2-Amino-5-methoxybenzoic acid, it is important to use appropriate personal protective equipment (PPE) such as gloves and goggles. It should be stored in a cool, dry place away from direct sunlight. In case of spill, avoid inhalation and contact with eyes or skin. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.