1-(2-{5-[(3-Methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl}-8-quinolinyl)-4-piperidinamine

Basic Information

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CAS Number

670220-88-9

Molecular Formula

C26H29N5O2

Molecular Weight

443.55 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Density

1.36

SMILES

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CC1(COC1)COC2=CC3=C(C=C2)N(C=N3)C4=NC5=C(C=CC=C5N6CCC(CC6)N)C=C4

InChI

InChI=1S/C26H29N5O2/c1-26(14-32-15-26)16-33-20-6-7-22-21(13-20)28-17-31(22)24-8-5-18-3-2-4-23(25(18)29-24)30-11-9-19(27)10-12-30/h2-8,13,17,19H,9-12,14-16,27H2,1H3

InChIKey

DYNHJHQFHQTFTP-UHFFFAOYSA-N

LogP

3.916500000000002

Topological Polar Surface Area

78.43 Å²

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

667

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

6T2
SCHEMBL2730601
SW218293-2
CP 868596
FT-0665221
LQF7I567TQ
C26H29N5O2
Crenolanib [USAN:INN]
CS-0566
Crenolanib (CP-868596)
Q5184160
SMR004702760
1-(2-{5-[(3-Methyloxetan-3-yl)methoxy]-1H-benzimidazol-1-yl}quinolin-8-yl)piperidin-4-amine
GTPL7882
CP868569
SB16603
CP-868596;CP 868596;CP868596;ARO 002
UNII-LQF7I567TQ
BDBM185149
CCG-264988
CP868596
[1-[2-[5-(3-Methyloxetan-3-ylmethoxy)benzimidazol-1-yl]quinolin-8-yl]piperidin-4-yl]amine
Crenolanib
1-(2-(5-((3-methyloxetan-3-yl)methoxy)-1H-benzo[d]imidazol-1-yl)quinolin-8-yl)piperidin-4-amine.
NSC800079
BCP02384
Crenolanib (USAN)
Crenolanib [USAN]
1-(2-{5-[(3-methyloxetan-3-yl)methoxy]-1H-1,3-benzodiazol-1-yl}quinolin-8-yl)piperidin-4-amine
CRENOLANIB [WHO-DD]
SY237889

MDL Number

MFCD21609260

FAQ

What regulatory guidelines apply to 1-(2-{5-[(3-Methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl}-8-quinolinyl)-4-piperidinamine (CAS: 670220-88-9)?

1-(2-{5-[(3-Methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl}-8-quinolinyl)-4-piperidinamine (CAS: 670220-88-9) falls under the scope of the REACH Regulation in the European Union. It may also require classification and labeling under the GHS (Globally Harmonized System of Classification and Labeling of Chemicals). In the US, it would need to comply with FDA requirements for chemical substances and the EPA for environmental and safety regulations.

Are there alternatives to 1-(2-{5-[(3-Methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl}-8-quinolinyl)-4-piperidinamine (CAS: 670220-88-9) in synthesis?

For the synthesis of 1-(2-{5-[(3-Methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl}-8-quinolinyl)-4-piperidinamine (CAS: 670220-88-9), alternative reagents such as related piperidines, benzimidazoles, and quinolines can be considered. Isomers and analogs like 1-(2-{5-[(3-Ethyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl}-8-quinolinyl)-4-piperidinamine may also serve as viable alternatives based on the specific synthetic route and desired properties.

What is the market or research trend for 1-(2-{5-[(3-Methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl}-8-quinolinyl)-4-piperidinamine (CAS: 670220-88-9)?

The research trend for 1-(2-{5-[(3-Methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl}-8-quinolinyl)-4-piperidinamine (CAS: 670220-88-9) indicates growing interest in its potential applications in pharmaceuticals and medicinal chemistry. Market trends suggest increasing demand due to its unique chemical structure and pharmacological activity. Emerging research focuses on its use as a potential therapeutic agent for various diseases, such as cancer and neurodegenerative disorders.

How should waste containing 1-(2-{5-[(3-Methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl}-8-quinolinyl)-4-piperidinamine (CAS: 670220-88-9) be handled?

Waste containing 1-(2-{5-[(3-Methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl}-8-quinolinyl)-4-piperidinamine (CAS: 670220-88-9) should be collected in appropriate containers and disposed of by incineration or professional waste disposal services. Environmental protection measures include proper labeling of waste containers, adherence to local waste disposal regulations, and monitoring of environmental impact to ensure compliance with regulatory standards and safety guidelines.

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Compound Q&A

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Compound Q&A

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Compound Q&A

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1-(2-{5-[(3-Methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl}-8-quinolinyl)-4-piperidinamine | CAS No. 670220-88-9

Basic Information

CAS Number

Molecular Formula

Molecular Weight

Chemical Classification

Basic Physical Properties

Density

Chemical Properties

SMILES

InChI

InChIKey

LogP

Topological Polar Surface Area

Hydrogen Bond Donor/Acceptor

Complexity

Safety Information

Hazard Statement

Synonyms & References

English

MDL Number

FAQ

What regulatory guidelines apply to 1-(2-{5-[(3-Methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl}-8-quinolinyl)-4-piperidinamine (CAS: 670220-88-9)?

Are there alternatives to 1-(2-{5-[(3-Methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl}-8-quinolinyl)-4-piperidinamine (CAS: 670220-88-9) in synthesis?

What is the market or research trend for 1-(2-{5-[(3-Methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl}-8-quinolinyl)-4-piperidinamine (CAS: 670220-88-9)?

How should waste containing 1-(2-{5-[(3-Methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl}-8-quinolinyl)-4-piperidinamine (CAS: 670220-88-9) be handled?

Related Compounds

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