EGTA (Ethylene glycol-bis(2-Aminoethyl Ether)-N,N,N',N'-tetra-Acetic Acid)

Basic Information

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CAS Number

67-42-5

Molecular Formula

C14H24N2O10

Molecular Weight

380.35 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

241 °C (dec.)

Boiling Point

678℃/760mmHg

Density

1.2838 (rough estimate)

Flash Point

363.9℃

Solubility

0.1 M NaOH: 0.1 M at 20 °C, clear, colorless

Refractive Index

1.4590 (estimate)

SMILES

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C(COCCOCCN(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O

InChI

InChI=1S/C14H24N2O10/c17-11(18)7-15(8-12(19)20)1-3-25-5-6-26-4-2-16(9-13(21)22)10-14(23)24/h1-10H2,(H,17,18)(H,19,20)(H,21,22)(H,23,24)

InChIKey

DEFVIWRASFVYLL-UHFFFAOYSA-N

LogP

-2.037999999999994

Topological Polar Surface Area

174.13999999999996 Å²

Hydrogen Bond Donor/Acceptor

4 / 12

Complexity

397

Safety Information

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GHS Hazard Pictograms

H303

Hazard Statement

H303 May be harmful if swallowed
Acute toxicity, oral

Sensitiveness

Sensitive to moisture

Synonyms & References

English

Egtazic acid
HY-D0861
Ethylene glycol-O,O'-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid, EGTA
ethylene glycol-bis(.beta.-aminoethyl ether)-n,n,n',n'-tetraacetic acid
ethylene glycol-bis(2-aminoethylether)-n,n,n,n-tetraacetic acid
Egtazic acid [USAN:INN]
EGTA; Egtazic acid
NCGC00015416-05
1,2-Bis[2-[bis(carboxymethyl)amino]ethoxy]ethane
E0805
Acidum egtazicum
Ethylenebis(oxyethylenenitrilo)tetraacetic acid
NCGC00015416-06
Ethylene glycol-bis(2-aminoethyl)-N,N,N',N'-tetraacetic acid
Ethylene glycol bis(b-aminoethyl ether)-N,N,N',N'-tetraacetic acid
CS-0015171
3,12-Bis(carboxymethyl)-6,9-dioxa-3,12-diazatetradecane-1,14-dioic acid
Ethylene glycol bis(aminoethyl ether)tetraacetate
EU-0100512
2-[2-[2-[2-[bis(carboxymethyl)amino]ethoxy]ethoxy]ethyl-(carboxymethyl)amino]acetic acid
6,9-Dioxa-3,12-diazatetradecanedioic acid, 3,12-bis(carboxymethyl)-
C14-H24-N2-O10
UNII-526U7A2651
EGTA [MI]
NCGC00261197-01
HB4708
ethylenbis(oxyethylennitrilo)tetraeddikesyre
Lopac-E-4378
Ethylene glycol bis(2-aminoethyl ether)tetraacetic acid
Ethylene glycol bis(beta-aminoethyl ether)-N,N'-tetraacetic acid
Gedta

MDL Number

MFCD00004291

Customs Code

29225000

FAQ

What is EGTA (CAS: 67-42-5)?

EGTA, or Ethylene glycol-bis(2-Aminoethyl Ether)-N,N,N',N'-tetra-Acetic Acid, is a chelating agent widely used in scientific research. It has the chemical formula C10H18N2O8 and is known for its high affinity for calcium ions. EGTA is a colorless solid that is soluble in water and is commonly used to sequester metal ions in biological systems and laboratory experiments.

What are the main uses of EGTA (CAS: 67-42-5)?

EGTA is primarily used in pharmaceutical research, biochemistry, and molecular biology. It serves as a calcium chelator, helping to control calcium ion concentrations in cell cultures, enzyme assays, and drug development. Additionally, EGTA is employed in industrial applications for metal ion removal and in food science for stabilizing certain compounds. Its utility in research is further supported by its role in fluorescence spectroscopy and ion channel studies.

Is EGTA (CAS: 67-42-5) safe?

EGTA is generally considered safe when handled properly, but it can be toxic if ingested or inhaled in large quantities. It is important to follow safety protocols such as wearing gloves, goggles, and a lab coat. EGTA is not classified as a hazardous substance under common safety standards, but appropriate protective measures should still be taken to ensure safe handling and disposal.

How should EGTA (CAS: 67-42-5) be stored?

EGTA should be stored in a cool, dry place away from direct light. It is typically kept in airtight containers to prevent moisture absorption and degradation. The recommended storage temperature is between 2-8°C, and it should be protected from humidity to maintain its stability and effectiveness over time.