N~2~-[(Benzyloxy)carbonyl]-N~6~-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine

Basic Information

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CAS Number

66845-42-9

Molecular Formula

C19H28N2O6

Molecular Weight

380.44 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

61-63°C

Boiling Point

587°C at 760 mmHg

Density

1.1760

Flash Point

308.8°C

Refractive Index

1.524

SMILES

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CC(C)(C)OC(=O)NCCCCC(C(=O)O)NC(=O)OCC1=CC=CC=C1

InChI

InChI=1S/C19H28N2O6/c1-19(2,3)27-17(24)20-12-8-7-11-15(16(22)23)21-18(25)26-13-14-9-5-4-6-10-14/h4-6,9-10,15H,7-8,11-13H2,1-3H3,(H,20,24)(H,21,25)(H,22,23)/t15-/m1/s1

InChIKey

DYSBKEOCHROEGX-OAHLLOKOSA-N

LogP

3.061000000000001

Topological Polar Surface Area

113.96000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 8

Complexity

483

Synonyms & References

English

N-BENZYLOXYCARBONYL-N-EPSILON-TERT-BUTOXYCARBONYL-L-LYSINE
Z-D-Lys(Boc)-OH, >=98.0% (TLC)
DTXSID40428486
(R)-2-(((benzyloxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoic acid
N
N6-[(1,1-Dimethylethoxy)carbonyl]-N2-[(phenylmethoxy)carbonyl]-D-lysine
(2R)-6-[(2-methylpropan-2-yl)oxycarbonylamino]-2-(phenylmethoxycarbonylamino)hexanoic acid
N-alpha-BenZyloxycarbonyl-N-epsilon-t-butyloxycarbonyl-D-lysine (CbZ-D-Lys(Boc)-OH)
N2-((Benzyloxy)carbonyl)-N6-(tert-butoxycarbonyl)-D-lysine
Z-D-Lys-(Boc)-OH
SCHEMBL2467817
F10986
DS-13754
MFCD00065699
AC-8575
Z-D-Lys(Boc)-OH
DYSBKEOCHROEGX-OAHLLOKOSA-N
HY-W008359
Q-101583
A-Boc-D-lysine
CS-W008359
AKOS015841476
(R)-2-(benzyloxycarbonylamino)-6-(tert-butoxycarbonylamino)hexanoic acid
A-Z-N
66845-42-9
J-300180
CBZ-D-LYS(BOC)-OH
N-Benzyloxycarbonyl-N'-(tert-Butoxycarbonyl)-L-lysine
Cbz-D-Lys(Boc)-OH
Nα-Z-Nε-Boc-D-lysine
N-ALPHA-CBZ-N-EPSILON-BOC-D-LYSINE

MDL Number

MFCD00065699

FAQ

What are the physical and chemical properties of N~2~-[(Benzyloxy)carbonyl]-N~6~-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine (CAS: 66845-42-9)?

N~2~-[(Benzyloxy)carbonyl]-N~6~-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine (CAS: 66845-42-9) is a white crystalline powder with a high molecular weight of approximately 512.6 g/mol and a melting point of around 190-195°C. It is slightly soluble in water but soluble in organic solvents. This compound is highly reactive, especially under acidic conditions, making it suitable for a variety of chemical reactions.

How is N~2~-[(Benzyloxy)carbonyl]-N~6~-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine (CAS: 66845-42-9) typically synthesized?

N~2~-[(Benzyloxy)carbonyl]-N~6~-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine (CAS: 66845-42-9) is typically synthesized via a multi-step process involving the protection of the lysine amino group with a benzyloxycarbonyl group, followed by the introduction of a 2-methyl-2-propanol group. The reaction conditions and catalysts used depend on the specific needs of the synthesis, aiming for high yields and selectivity.

What industries use N~2~-[(Benzyloxy)carbonyl]-N~6~-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine (CAS: 66845-42-9)?

N~2~-[(Benzyloxy)carbonyl]-N~6~-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine (CAS: 66845-42-9) is primarily used in the pharmaceutical industry for the development of synthetic peptides and in the polymer industry for the synthesis of custom polymers. It is also utilized in the production of certain sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling N~2~-[(Benzyloxy)carbonyl]-N~6~-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine (CAS: 66845-42-9)?

When handling N~2~-[(Benzyloxy)carbonyl]-N~6~-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-lysine (CAS: 66845-42-9), appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat should be worn. This compound should be handled in a fume hood to minimize exposure. Spills should be cleaned up carefully using appropriate methods and all waste should be disposed of according to local regulations. Always refer to the safety data sheet (SDS) for detailed handling instructions.