1-Amino Adamantane HCl (Amantadine HCl)

Basic Information

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CAS Number

665-66-7

Molecular Formula

C10H18ClN

Molecular Weight

187.71 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Melting Point

300 ºC

Boiling Point

308.63°C (rough estimate)

Density

1.0276 (rough estimate)

Flash Point

96℃

Solubility

H2O: 50 mg/mL

Refractive Index

1.6100 (estimate)

SMILES

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Cl.NC1(CC2CC3CC(C2)C1)C3

InChI

InChI=1S/C10H17N.ClH/c11-10-4-7-1-8(5-10)3-9(2-7)6-10;/h7-9H,1-6,11H2;1H

InChIKey

WOLHOYHSEKDWQH-UHFFFAOYSA-N

LogP

2.3357

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

144

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Hazard Class

Class IRRITANT Class IRRITANT

Sensitiveness

Hygroscopic

Toxicity

LD50 orally in mice, rats: 700, 1275 mg/kg (Vernier)

Synonyms & References

English

1-Adamantanamine hydrochloride
1-Aminoadamantane hydrochloride
Amantadine hydrochloride
AMANTADINE HCL
1-Adamantylamine hydrochloride
Adamantanaminehydrochloride
1-adamantamine hydrochloride
Adekin
Amazolon
exp105-1
Lysovir
Mantadan
Mantadix
Midantan
virasol
Virofral
Nicotine hydrochloride
NSC 83653
Tricyclo[3.3.1.13,7]decan-1-amine hydrochloride
Symmetrel
Mydantane
Midantane
adamantan-1-amine hydrochloride
Adamantanamine hydrochloride
Trivaline
Influenol
Viregyt
Amantan
Virosol
Adamantylamine hydrochloride
Aminoadamantane hydrochloride

MDL Number

MFCD00074723

Customs Code

2921300090

FAQ

What is 1-Amino Adamantane HCl (CAS: 665-66-7)?

1-Amino Adamantane HCl, also known as Amantadine HCl, is a chemical compound with the CAS number 665-66-7. It is a derivative of adamantane, featuring an amino group and hydrochloride salt. This compound is known for its crystalline structure and is commonly used in pharmaceutical applications. It has a molecular formula of C13H20ClN and is characterized by its stability and low solubility in water.

What are the main uses of 1-Amino Adamantane HCl (CAS: 665-66-7)?

1-Amino Adamantane HCl is primarily used in the pharmaceutical industry as an antiviral and antiparkinsonian agent. It is also employed in research for its neuroprotective properties and in the synthesis of other compounds. Additionally, it may find applications in industrial processes and as a component in certain formulations due to its chemical stability and unique structure.

Is 1-Amino Adamantane HCl (CAS: 665-66-7) safe?

1-Amino Adamantane HCl is generally considered safe when used under proper guidance and in accordance with safety standards. However, it should be handled with care, as high concentrations may cause irritation. Protective measures such as gloves and ventilation are recommended. Safety data sheets (SDS) should be consulted for detailed information on toxicity and handling precautions.

How should 1-Amino Adamantane HCl (CAS: 665-66-7) be stored?

1-Amino Adamantane HCl should be stored in a cool, dry, and dark place, preferably at temperatures below 25°C. It is stable under these conditions and should be kept in a sealed container to prevent moisture absorption. Avoid exposure to light and maintain low humidity to ensure its chemical integrity and prolong shelf life.