4-[(1S)-3-(Methylamino)-1-(2-thienyl)propoxy]-1-naphthol | CAS No. 662149-13-5

4-[(1S)-3-(Methylamino)-1-(2-thienyl)propoxy]-1-naphthol

Basic Information

CAS Number

662149-13-5

Molecular Formula

C18H19NO2S

Molecular Weight

313.42 g/mol

AD

Basic Physical Properties

Melting Point

140-143°C

CNCC[C@@H](c1cccs1)Oc1ccc(c2c1cccc2)O

InChI

InChI=1S/C18H19NO2S/c1-19-11-10-17(18-7-4-12-22-18)21-16-9-8-15(20)13-5-2-3-6-14(13)16/h2-9,12,17,19-20H,10-11H2,1H3/t17-/m0/s1

InChIKey

DRRXQCXSBONKPD-KRWDZBQOSA-N

LogP

4.3365000000000045

Topological Polar Surface Area

41.489999999999995 Ų

Hydrogen Bond Donor/Acceptor

2 / 3

Synonyms & References

English

  • 4-Hydroxy Duloxetine
  • 4-[(1S)-3-(methylamino)-1-thiophen-2-ylpropoxy]naphthalen-1-ol
  • 4-[(1S)-3-(METHYLAMINO)-1-(2-THIENYL)PROPOXY]-1-NAPHTHALENOL

MDL Number

MFCD09952221

FAQ

What regulatory guidelines apply to 4-[(1S)-3-(Methylamino)-1-(2-thienyl)propoxy]-1-naphthol (CAS: 662149-13-5)?

The compound 4-[(1S)-3-(Methylamino)-1-(2-thienyl)propoxy]-1-naphthol (CAS: 662149-13-5) falls under the scope of REACH regulations in the EU. It is also subject to the Globally Harmonized System of Classification and Labeling of Chemicals (GHS) for hazard communication. For specific handling and disposal, the FDA and EPA may have additional requirements, particularly if the compound is intended for pharmaceutical or environmental applications.

Are there alternatives to 4-[(1S)-3-(Methylamino)-1-(2-thienyl)propoxy]-1-naphthol (CAS: 662149-13-5) in synthesis?

Alternatives to 4-[(1S)-3-(Methylamino)-1-(2-thienyl)propoxy]-1-naphthol (CAS: 662149-13-5) in synthesis include similar compounds such as 4-[(1R)-3-(Methylamino)-1-(2-thienyl)propoxy]-1-naphthol and analogs like 4-[(1S)-3-(Methylamino)-1-(3-thienyl)propoxy]-1-naphthol. Common alternative reagents in synthesis include thiosemicarbazides and thiazols.

What is the market or research trend for 4-[(1S)-3-(Methylamino)-1-(2-thienyl)propoxy]-1-naphthol (CAS: 662149-13-5)?

The market trend for 4-[(1S)-3-(Methylamino)-1-(2-thienyl)propoxy]-1-naphthol (CAS: 662149-13-5) is driven by its potential applications in pharmaceuticals and materials science. Research trends focus on its biological activity and chemical reactivity. Recent studies highlight its use as an intermediate in the synthesis of new drugs and its properties in developing advanced coatings and adhesives.

How should waste containing 4-[(1S)-3-(Methylamino)-1-(2-thienyl)propoxy]-1-naphthol (CAS: 662149-13-5) be handled?

Waste containing 4-[(1S)-3-(Methylamino)-1-(2-thienyl)propoxy]-1-naphthol (CAS: 662149-13-5) should be collected in appropriate containers and stored under controlled conditions to prevent degradation. Proper incineration or professional waste disposal services should be utilized for final disposal. Environmental protection measures, such as minimizing the release of toxic substances, should be followed to ensure compliance with local regulations and environmental standards.

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