Tyrphostin AG 1024

Basic Information

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CAS Number

65678-07-1

Molecular Formula

C14H13BrN2O

Molecular Weight

305.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Nitriles

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

379.8°C at 760 mmHg

Density

1.420±0.06 g/cm3 (20 ºC 760 Torr),

SMILES

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CC(C)(C)C1=C(C(=CC(=C1)C=C(C#N)C#N)Br)O

InChI

InChI=1S/C14H13BrN2O/c1-14(2,3)11-5-9(4-10(7-16)8-17)6-12(15)13(11)18/h4-6,18H,1-3H3

InChIKey

ABBADGFSRBWENF-UHFFFAOYSA-N

LogP

3.88276

Complexity

414

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

2-(3-Bromo-5-(tert-butyl)-4-hydroxybenzylidene)malononitrile
AG-1024
2-(3-Bromo-5-tert-butyl-4-hydroxybenzylidene)malononitrile
2-[(3-bromo-5-tert-butyl-4-hydroxyphenyl)methylidene]propanedinitrile
AG 1024
AG-1024 (Tyrphostin)
(3-bromo-5-tert-butyl-4-hydroxybenzylidene)malononitrile
3-Bromo-5-t-butyl-4-hydroxy-benzylidenemalonitrile
3-bromo-5-t-butyl-4-hydroxy-benzylidene-malononitrile
propanedinitrile,[[3-bromo-5-(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]
AGS 200
Tyrphostin AG 1024
ag1024
propanedinitrile, [[3-bromo-5-(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]-
ABBADGFSRBWENF-UHFFFAOYSA-N
A
AG1024
EX-A1791
HMS3654L05
DA-70633
2-[[3-Bromo-5-(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]propanedinitrile
S1234
CHEBI:93757
BDBM50198773
HSCI1_000032
CHEMBL2218926
Q27074330
CCG-101297
NF4XN6A8V9
HMS3229A03
HY-10253

MDL Number

Molecular Weight

Customs Code

2926909090

FAQ

What is Tyrphostin AG 1024 (CAS: 65678-07-1)?

Tyrphostin AG 1024 (CAS: 65678-07-1) is a selective inhibitor of receptor tyrosine kinases (RTKs), particularly targeting the epidermal growth factor receptor (EGFR). It is an organic compound with a molecular weight of approximately 348.34 g/mol and is soluble in organic solvents.

What are the main uses of Tyrphostin AG 1024 (CAS: 65678-07-1)?

Tyrphostin AG 1024 is primarily used in research for studying the effects of receptor tyrosine kinase inhibition and in the development of targeted cancer therapies. It is also utilized in preclinical studies to investigate the mechanisms of action of RTK inhibitors.

Is Tyrphostin AG 1024 (CAS: 65678-07-1) safe?

Tyrphostin AG 1024 (CAS: 65678-07-1) is generally considered safe for laboratory use with proper handling. However, it should be used with caution due to its potency. Ensure to follow all safety guidelines, including the use of personal protective equipment and proper waste disposal.

How should Tyrphostin AG 1024 (CAS: 65678-07-1) be stored?

Tyrphostin AG 1024 should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent moisture absorption. Store it at room temperature (15-25°C) and avoid exposure to excessive humidity.