(1R,2R)-1,2-Cyclohexanediyldimethanol

Basic Information

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CAS Number

65376-05-8

Molecular Formula

C8H16O2

Molecular Weight

144.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Hydrocarbons

Basic Physical Properties

Melting Point

63.0 to 67.0 deg-C

Boiling Point

113°C/0.2mmHg

Density

1.004

Flash Point

129 ºC

Refractive Index

1.47

SMILES

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C1CC[C@H]([C@@H](C1)CO)CO

InChI

InChI=1S/C8H16O2/c9-5-7-3-1-2-4-8(7)6-10/h7-10H,1-6H2/t7-,8-/m0/s1

InChIKey

XDODWINGEHBYRT-YUMQZZPRSA-N

LogP

0.7773999999999999

Topological Polar Surface Area

40.46 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

81.3

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(1R,2R)-Cyclohexane-1,2-diyldimethanol
Lurasidone INT 3
[(1R,2R)-2-(hydroxymethyl)cyclohexyl]methanol
(1R,2R)-1,2-CYCLOHEXANEDI
(1R,2R)-1,2-Cyclohexanedimethanol
(1R,2R)-1,2-Bis(hydroxymethyl)cyclohexane
1,2-CyclohexanediMethanol, (1R,2R)-
Lurasidone Intermediate I
(+)-(1R,2R)-trans-1,2-bis(hydroxymethyl)cyclohexane
(1R,2R)-(-)-pseudoephedrine glycinamide
(R)-trans-1,2-Bis-hydroxymethyl-cyclohexan
(R)-trans-1,2-bis-hydroxymethyl-cyclohexane
(R,R)-(-)-pseudoephedrine glycinamide hydrate
(R,R)-1,2-bis(hydroxymethyl)cyclohexane
1,2-bis(hydroxymethyl)cyclohexane
2-amino-N-((1R,2R)-1-hydroxy-1-phenylpropan-2-yl)-N-methylacetamide
pseudoephedrine glycinamide
trans-2-hydroxymethylcyclohexylmethanol
trans-Cyclohexane-1,2-diyldimethanol
trans-1,2-Cyclohexanedimethanol
1,2-Cyclohexanedimethanol, (1R-trans)-
1,2-Cyclohexanedimethanol, (1R,2R)-rel-
trans-1,2-Bis(hydroxymethyl)cyclohexane
(1S,2S)-1,2-CyclohexanediMethanol
trans-(Cyclohexane-1,2-diyl)dimethanol
XDODWINGEHBYRT

MDL Number

MFCD16660860

Customs Code

2906199090

FAQ

What is (1R,2R)-1,2-Cyclohexanediyldimethanol (CAS: 65376-05-8)?

(1R,2R)-1,2-Cyclohexanediyldimethanol (CAS: 65376-05-8) is a cyclic diol with the chemical formula C8H16O4. It is a colorless liquid with a slightly sweet odor, characterized by its stereochemistry (1R,2R) and solubility in organic solvents. This compound is commonly used as a precursor in polymer synthesis and chemical manufacturing due to its reactivity and structural versatility.

What are the main uses of (1R,2R)-1,2-Cyclohexanediyldimethanol (CAS: 65376-05-8)?

(1R,2R)-1,2-Cyclohexanediyldimethanol (CAS: 65376-05-8) is primarily utilized in pharmaceuticals as a building block for drug development, in industrial applications for producing polymeric materials, and in research for synthesizing complex organic compounds. It also serves as a solvent in certain chemical processes and is relevant in food additive formulations due to its chemical stability.

Is (1R,2R)-1,2-Cyclohexanediyldimethanol (CAS: 65376-05-8) safe?

(1R,2R)-1,2-Cyclohexanediyldimethanol (CAS: 65376-05-8) is generally considered safe when handled properly, but it may cause mild irritation to skin or eyes. Safety data sheets (SDS) recommend using appropriate protective equipment, such as gloves and goggles, during handling. It is non-toxic in normal use conditions but should be stored and used according to standard chemical safety guidelines to ensure minimal risk.

How should (1R,2R)-1,2-Cyclohexanediyldimethanol (CAS: 65376-05-8) be stored?

(1R,2R)-1,2-Cyclohexanediyldimethanol (CAS: 65376-05-8) should be stored in a cool, dry place (ideally below 25°C), protected from light, and in an airtight container to prevent moisture absorption. It remains stable under normal storage conditions but should be kept away from heat sources and incompatible materials to maintain its chemical integrity.