Methyl D-prolinate hydrochloride (1:1)

Basic Information

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CAS Number

65365-28-8

Molecular Formula

C6H12ClNO2

Molecular Weight

165.62 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

70.0 to 76.0 deg-C

Refractive Index

32 ° (C=1, H2O)

Specific Rotation

+32° (c=1, H2O)

SMILES

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COC(=O)C1CCCN1.Cl

InChI

InChI=1S/C6H11NO2.ClH/c1-9-6(8)5-3-2-4-7-5;/h5,7H,2-4H2,1H3;1H/t5-;/m1./s1

InChIKey

HQEIPVHJHZTMDP-NUBCRITNSA-N

LogP

0.3332

Topological Polar Surface Area

38.33 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

114

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Sensitiveness

Hygroscopic

Synonyms & References

English

HQEIPVHJHZTMDP-NUBCRITNSA-N
Methyl (R)-pyrrolidine-2-carboxylate hydrochloride
65365-28-8
Methyl D-prolinate hydrochloride
AS-12764
H-D-Pro-OMe.HCl
SCHEMBL1223341
Methyl D-prolinate--hydrogen chloride (1/1)
AM82197
D-Proline, methyl ester, hydrochloride
H-D-PRO-OME HCL
H-D-Pro.OMe.HCl
AKOS015924160
methyl (2R)-pyrrolidine-2-carboxylate hydrochloride
P1730
C15EPU1M46
UNII-C15EPU1M46
DTXSID50659784
Q27275045
(R)-pyrrolidine-2-carboxylic acid methyl ester hydrochloride
D-Proline Methyl Ester Hydrochloride
(R)-proline methyl ester hydrochloride
D-Proline Methyl Ester HCl
Methyl D-prolinate hydrochloride (1:1)
F10972
Methyl proline hydrochloride, (R)-
(R)-methyl pyrrolidine-2-carboxylate hydrochloride
CS-W000223
Pyrrolidine-2-carboxylic acid methyl ester; compound with methane
CS-W010818
MFCD00083685

MDL Number

MFCD00083685

FAQ

What regulatory guidelines apply to Methyl D-prolinate hydrochloride (CAS: 65365-28-8)?

Methyl D-prolinate hydrochloride (CAS: 65365-28-8) is subject to various regulatory guidelines. Under the Globally Harmonized System of Classification and Labeling of Chemicals (GHS), it may be classified as an irritant. In the European Union, it falls under the Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) regulations. The U.S. Food and Drug Administration (FDA) and Environmental Protection Agency (EPA) may also have specific requirements for its handling and disposal.

Are there alternatives to Methyl D-prolinate hydrochloride (CAS: 65365-28-8) in synthesis?

There are several alternatives to Methyl D-prolinate hydrochloride (CAS: 65365-28-8) in synthesis. Some common alternatives include methyl L-proline hydrochloride and other related proline derivatives. These alternatives can offer similar functionalities in different chemical reactions and are often chosen based on availability, cost, and specific reaction requirements.

What is the market or research trend for Methyl D-prolinate hydrochloride (CAS: 65365-28-8)?

The market for Methyl D-prolinate hydrochloride (CAS: 65365-28-8) is growing due to its applications in pharmaceuticals and agrochemicals. Research is focusing on its use as a chiral building block in asymmetric synthesis. Price trends are influenced by supply chain stability and demand from industries such as drug development and crop protection. Emerging research fields include its potential use in green chemistry and sustainable chemical processes.

How should waste containing Methyl D-prolinate hydrochloride (CAS: 65365-28-8) be handled?

Waste containing Methyl D-prolinate hydrochloride (CAS: 65365-28-8) should be collected in appropriate waste containers and stored separately. Proper incineration or professional waste disposal services should be used to ensure safe handling. Environmental protection precautions include ensuring no direct contact with water sources and following local regulations for hazardous waste disposal. It is recommended to consult with a chemical disposal expert for specific guidelines.