2,3-Dichloro-6-nitroaniline

Basic Information

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CAS Number

65078-77-5

Molecular Formula

C6H4Cl2N2O2

Molecular Weight

207.01 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

166.7 ºC

Boiling Point

323.5℃ at 760 mmHg

Density

1.624±0.06 g/cm3 (20 ºC 760 Torr),

SMILES

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Nc1c(Cl)c(Cl)ccc1[N+](=O)[O-]

InChI

InChI=1S/C6H4Cl2N2O2/c7-3-1-2-4(10(11)12)6(9)5(3)8/h1-2H,9H2

InChIKey

RDCOVUDTFKIURA-UHFFFAOYSA-N

LogP

3.58820

Complexity

185

Synonyms & References

English

Benzenamine,2,3-dichloro-6-nitro-
2,3-Dichloro-6-nitroaniline
2,3-Dichloro-6-nitrobenzenamine
Benzenamine, 2,3-dichloro-6-nitro-
RDCOVUDTFKIURA-UHFFFAOYSA-N
FCH1330152
AK205589
SY039015

MDL Number

MFCD00110529

FAQ

What are the physical and chemical properties of 2,3-Dichloro-6-nitroaniline (CAS: 65078-77-5)?

2,3-Dichloro-6-nitroaniline is a crystalline solid with a molecular weight of approximately 216.03 g/mol. It is slightly soluble in water and has a high solubility in organic solvents like ethanol and acetone. Chemically, it is highly reactive due to the presence of electron-withdrawing nitro and halogen substituents, which can participate in various electrophilic and nucleophilic reactions.

How is 2,3-Dichloro-6-nitroaniline (CAS: 65078-77-5) typically synthesized?

2,3-Dichloro-6-nitroaniline can be synthesized via the nitration of 2,3-dichlorobenzenamine followed by deamination. This process involves the use of nitric acid and sulfuric acid as reagents, with strict temperature control to ensure high yield and selectivity. Catalysts such as iron(III) nitrate are sometimes used to improve the reaction efficiency.

What industries use 2,3-Dichloro-6-nitroaniline (CAS: 65078-77-5)?

2,3-Dichloro-6-nitroaniline is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the production of dyes, pigments, and as an intermediate in the manufacturing of various organic compounds. Its role in sensors and semiconductors is less common but can be utilized in specialized applications.

What precautions should be taken when handling 2,3-Dichloro-6-nitroaniline (CAS: 65078-77-5)?

When handling 2,3-Dichloro-6-nitroaniline, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbents and washed down the sink with plenty of water. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.