Salicylamide | CAS No. 65-45-2

Q: What is Salicylamide (CAS: 65-45-2)?

Salicylamide is an organic compound with the chemical formula C7H7NO2. It is a white crystalline solid that is soluble in water and commonly used in pharmaceutical applications. It is known for its analgesic and anti-inflammatory properties and serves as a precursor in the synthesis of various drugs.

Q: What are the main uses of Salicylamide (CAS: 65-45-2)?

Salicylamide is primarily used in the pharmaceutical industry as an analgesic and antipyretic agent. It is also employed in the production of drugs like aspirin and other salicylate derivatives. Additionally, it finds applications in industrial processes, such as the synthesis of dyes and pesticides, and is used in research for its chemical reactivity and utility in organic synthesis.

Q: Is Salicylamide (CAS: 65-45-2) safe?

Salicylamide is generally considered safe when used as directed, but it can cause toxicity if ingested in large amounts or mishandled. Proper protective measures, such as gloves and safety goggles, should be used during handling. It is important to follow safety standards and guidelines to prevent adverse effects, especially in industrial and laboratory settings.

Q: How should Salicylamide (CAS: 65-45-2) be stored?

Salicylamide should be stored in a cool, dry, and well-ventilated area, away from light and moisture. It is best kept in a sealed container to maintain its stability and prevent degradation. Storage at temperatures below 25°C is recommended to ensure long-term quality and safety.

Salicylamide

Basic Information

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CAS Number

65-45-2

Molecular Formula

C7H7NO2

Molecular Weight

137.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

140-144 °C

Boiling Point

182°C/14mmHg

Density

1,175 g/cm3

Water Solubility

<0.1 g/100 mL at 20 ºC

Flash Point

181°C/14mm

Solubility

methanol: 0.1 g/mL, clear

Refractive Index

1.5323 (estimate)

Vapor Pressure

0.0±0.7 mmHg at 25°C

SMILES

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NC(=O)c1ccccc1O

InChI

InChI=1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10)

InChIKey

SKZKKFZAGNVIMN-UHFFFAOYSA-N

LogP

0.49110000000000004

Topological Polar Surface Area

63.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

136

Safety Information

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GHS Hazard Pictograms

H302

H315

H319

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1(b) Class 6.1(b)

Stability

Stable. Light sensitive. Incompatible with strong bases, strong oxidizing agents.

Sensitiveness

光 sensitive

Toxicity

LD50 orally in mice: 1.4 g/kg (Hart)

Synonyms & References

English

2-Hydroxybenzamide
2-Carbamoylphenol
2-hydroxy-benzamid
2-hydroxy-benzoicaciamide
Acket
Afko-Sal
Algamon
Algiamida
Allevin
Amid kyseliny salicylove
Amidosal
Amid-Sal
Anamid
Andasol
Benesal
Salicylamide
2-hydroxy-benzamide
Benzamide,2-hydroxy
hydroxybenzamide
hydroxyphenylamide
ortho-hydroxybenzamide
SalaMide
Salicylic acid amide
o-Hydroxybenzamide
Benzamide, 2-hydroxy-
Morsarinas
Flarpirina
Raspberin
Novecyl
Dropsprin
Urtosal

MDL Number

MFCD00007978

Customs Code

2924299090

FAQ

What is Salicylamide (CAS: 65-45-2)?

Salicylamide is an organic compound with the chemical formula C7H7NO2. It is a white crystalline solid that is soluble in water and commonly used in pharmaceutical applications. It is known for its analgesic and anti-inflammatory properties and serves as a precursor in the synthesis of various drugs.

What are the main uses of Salicylamide (CAS: 65-45-2)?

Salicylamide is primarily used in the pharmaceutical industry as an analgesic and antipyretic agent. It is also employed in the production of drugs like aspirin and other salicylate derivatives. Additionally, it finds applications in industrial processes, such as the synthesis of dyes and pesticides, and is used in research for its chemical reactivity and utility in organic synthesis.

Is Salicylamide (CAS: 65-45-2) safe?

Salicylamide is generally considered safe when used as directed, but it can cause toxicity if ingested in large amounts or mishandled. Proper protective measures, such as gloves and safety goggles, should be used during handling. It is important to follow safety standards and guidelines to prevent adverse effects, especially in industrial and laboratory settings.

How should Salicylamide (CAS: 65-45-2) be stored?

Salicylamide should be stored in a cool, dry, and well-ventilated area, away from light and moisture. It is best kept in a sealed container to maintain its stability and prevent degradation. Storage at temperatures below 25°C is recommended to ensure long-term quality and safety.