Phentolamine mesylate

Basic Information

View in Editor

CAS Number

65-28-1

Molecular Formula

C18H23N3O4S

Molecular Weight

377.47 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

180-182 °C

Boiling Point

551°C at 760 mmHg

Density

1.2256 (rough estimate)

Water Solubility

50 mg/mL

Flash Point

287°C

Solubility

ethanol: 26 mg/mL

Refractive Index

1.6320 (estimate)

Vapor Pressure

No data available

SMILES

View in Editor

Cc1ccc(cc1)N(CC2=NCCN2)c3cccc(O)c3.CS(=O)(=O)O

InChI

InChI=1S/C17H19N3O.CH4O3S/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15;1-5(2,3)4/h2-8,11,21H,9-10,12H2,1H3,(H,18,19);1H3,(H,2,3,4)

InChIKey

OGIYDFVHFQEFKQ-UHFFFAOYSA-N

LogP

2.3444199999999995

Topological Polar Surface Area

102.23 Å²

Hydrogen Bond Donor/Acceptor

3 / 7

Complexity

1950

Safety Information

View Safety Information

GHS Hazard Pictograms

H302

H312

H315

H319

H332

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1(b) Class 6.1(b)

Stability

Aq. Solutions Cannot be Stored

Synonyms & References

English

PHENTOLAMINE MESYLATE
REGITIN
REGITIN MESYLATE
PHENTOLAMINE MESILATE
PHENTOLAMINE METHANESULFONATE
PHENTOLAMINE METHANESULFONATE SALT
VASOMAX
m-(n-(2-imidazolin-2-ylmethyl)-p-toluidino)-phenomonomethanesulfonate(sal
Phentolamine (mesylate)
Phentolamine Methane
2-[N-(m-Hydroxyphenyl)-p-toluidinomethyl]imidazoline Methanesulfonate
3-[N-(2-Imidazolin-2-ylmethyl)-p-toluidino]phenol methanesulphonate
3,6,9,23,26,29,32,35,49,52,55,69,72,75,78,81,84-Heptadecaoxatridecacyclo[65.28.1.111,37.121,47.157,8
Phentolamine methanesulfonate
Phentolamine Methanesulfonate
Phentolamine methanesulfonate salt
Phentolamine mesylate
3-(((4,5-Dihydro-1H-imidazol-2-yl)methyl)(p-tolyl)amino)phenol
methanesulfonate (1:1)

MDL Number

MFCD00134201

Customs Code

2933290090

FAQ

What is Phentolamine mesylate (CAS: 65-28-1)?

Phentolamine mesylate is a chemical compound with the CAS number 65-28-1. It is a mesylate salt of phentolamine, which is an alpha-adrenergic antagonist. This compound is commonly used in pharmaceutical applications and has a molecular formula of C12H17NO4S. It is a white to pale yellow crystalline powder, soluble in water and alcohol, and exhibits stability under normal conditions.

What are the main uses of Phentolamine mesylate (CAS: 65-28-1)?

Phentolamine mesylate is primarily used in pharmaceuticals as a vasodilator and antihypertensive agent. It is also applied in research for its role in blocking alpha-adrenergic receptors. Additionally, it may be used in industrial settings for chemical synthesis and in laboratory environments for various experimental purposes. Its versatility makes it a valuable compound in multiple fields.

Is Phentolamine mesylate (CAS: 65-28-1) safe?

Phentolamine mesylate is generally considered safe when used as directed, but it requires proper handling to ensure safety. It is not classified as highly toxic, but skin contact and inhalation should be avoided. Protective gloves and masks are recommended during handling. Safety standards for its use are typically governed by OSHA and REACH regulations, emphasizing the importance of following safety guidelines in both industrial and laboratory settings.

How should Phentolamine mesylate (CAS: 65-28-1) be stored?

Phentolamine mesylate should be stored in a cool, dry place away from direct light. It is stable at room temperature (15-25°C) and should be kept in a sealed container to prevent moisture absorption. Proper storage conditions are essential to maintain its chemical integrity and effectiveness. Avoid exposure to high humidity and ensure it is stored in a well-ventilated area.