Yohimbine HCl

Basic Information

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CAS Number

65-19-0

Molecular Formula

C21H27ClN2O3

Molecular Weight

390.91 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

285-290 ºC

Boiling Point

542.979°C at 760 mmHg

Flash Point

282.184℃

Solubility

H2O: 10 mg/mL

Refractive Index

103 ° (C=1, H2O)

Specific Rotation

99 º (c=1%, H2O, dry subst)

SMILES

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COC(=O)C1C(CCC2C1CC3C4=C(CCN3C2)C5=CC=CC=C5N4)O.Cl

InChI

InChI=1S/C21H26N2O3.ClH/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24;/h2-5,12,15,17-19,22,24H,6-11H2,1H3;1H/t12-,15-,17-,18-,19+;/m0./s1

InChIKey

PIPZGJSEDRMUAW-VJDCAHTMSA-N

LogP

3.068900000000003

Topological Polar Surface Area

65.56 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

555

Safety Information

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GHS Hazard Pictograms

H300

H311

H331

Hazard Statement

H300 Fatal if swallowed
Acute toxicity, oral

H311 Toxic in contact with skin
Acute toxicity, dermal

H331 Toxic if inhaled
Acute toxicity, inhalation

Hazard Class

Class 6.1 Class 6.1

Storage Conditions

2-8℃

Sensitiveness

Light Sensitive

Synonyms & References

English

Yohimban-16alpha-carboxylic acid, 17alpha-hydroxy-, methyl ester, monohydrochloride
Yohimbine hydrochloride, analytical standard
Tox21_501210
LP01210
Yohimbine hydrochloride (USP)
AKOS015951349
17alpha-Hydroxy-20-alpha-yohimban-16-beta-carboxylic acid, methyl ester, hydrochloride
YOHIMBINE HYDROCHLORIDE [USP MONOGRAPH]
Yohimbine HCl
DTXSID40891272
17.ALPHA.-HYDROXY-20-.ALPHA.-YOHIMBAN-16-.BETA.-CARBOXYLIC ACID, METHYL ESTER, HYDROCHLORIDE
YOHIMBINE CHLORIDE
65-19-0 (HCL)
65-19-0
Gynimbine
Aphrodine hydrochloride
YOHIMBINE HYDROCHLORIDE [WHO-DD]
SR-01000597896-4
NCGC00094457-01
Y 3125
Q15680050
MLS001333983
BCP19708
YOHIMBINE HYDROCHLORIDE
NIH 9689
Aphrodyne
Antagonil
SW199050-2
17-Hydroxyyohimban-16-carboxylic acid methyl ester hydrochloride
AC-22571
Dayto-Himbin

MDL Number

MFCD00012674

FAQ

What is Yohimbine HCl (CAS: 65-19-0)?

Yohimbine HCl is a compound with the chemical formula C21H32N2O4. It is a hydrochloride salt of yohimbine, a natural alkaloid derived from the bark of the African tree *Pausinystalia yohimbe*. Yohimbine HCl is known for its stimulant and alpha-2 adrenergic receptor antagonist properties, making it relevant in pharmaceutical and research contexts.

What are the main uses of Yohimbine HCl (CAS: 65-19-0)?

Yohimbine HCl is primarily used in pharmaceuticals as a research tool and in the treatment of erectile dysfunction. It also finds applications in the study of neurotransmission, weight management, and as a stimulant in some dietary supplements. Its uses are supported by its pharmacological activity and clinical research relevance.

Is Yohimbine HCl (CAS: 65-19-0) safe?

Yohimbine HCl is generally considered safe when used as directed, but it may cause side effects such as increased heart rate, anxiety, and insomnia. It is important to handle it with care, follow safety guidelines, and consult healthcare professionals before use, especially for individuals with pre-existing medical conditions or those on medication.

How should Yohimbine HCl (CAS: 65-19-0) be stored?

Yohimbine HCl should be stored in a cool, dry place away from direct light. It is typically kept in a sealed container at a temperature between 15°C to 25°C. Maintaining proper humidity levels and ensuring the container is airtight will help preserve the stability and potency of the compound over time.