(2R)-1-({4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl}oxy)-2-propanol | CAS No. 649735-46-6

(2R)-1-({4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl}oxy)-2-propanol

Basic Information

CAS Number

649735-46-6

Molecular Formula

C19H19FN4O3

Molecular Weight

370.38 g/mol

AD

Basic Physical Properties

Density

1.42

Refractive Index

1.66

Cc1cc2c([nH]1)ccc(c2F)Oc3c4c(c(cn4ncn3)OC[C@@H](C)O)C

InChI

InChI=1S/C19H19FN4O3/c1-10-6-13-14(23-10)4-5-15(17(13)20)27-19-18-12(3)16(26-8-11(2)25)7-24(18)22-9-21-19/h4-7,9,11,23,25H,8H2,1-3H3/t11-/m1/s1

InChIKey

WCWUXEGQKLTGDX-LLVKDONJSA-N

LogP

3.518440000000002

Topological Polar Surface Area

84.67 Ų

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

515

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H317 May cause an allergic skin reaction
Sensitization, Skin

Synonyms & References

English

  • Brivanib
  • Tyrosine Kinase Inhibitor
  • 1-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol
  • Brivanib (BMS-540215)
  • (2R)-1-[4-(4-Fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy]propanol
  • (2R)-1-[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methyl-pyrrolo[2,1-f][1,2,4]triazin-6-yl]oxypropan-2-ol
  • (2R)-1-[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxypropan-2-ol
  • (R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[1,2-f][1,2,4]triazin-6-yloxy)propan-2-ol
  • 1-[[4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo-[2,1-f][1,2,4]triazin-6-yl]oxy]-2-propanol
  • Bms 540215
  • BMS-540215
  • Brivanib [USAN]
  • BMS540215
  • DDU33B674I
  • Brivanib (USAN)
  • (2R)-1-({4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl}oxy)propan-2-ol
  • (R)-1-(4-(4-Fluoro-2-methyl-1H-indol-

MDL Number

MFCD13194684

Customs Code

2933990090

FAQ

What is (2R)-1-({4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl}oxy)-2-propanol (CAS: 649735-46-6)?

It is a complex organic compound with a unique molecular structure, consisting of a propanol group attached to a pyrrolo[2,1-f][1,2,4]triazin-6-yl derivative containing a fluoro-indol moiety. This compound is characterized by its aromatic and heterocyclic nature, which contributes to its potential biological activity.

What are the main uses of (2R)-1-({4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl}oxy)-2-propanol (CAS: 649735-46-6)?

This compound has shown potential in pharmaceutical applications, particularly as a candidate for further research into anticancer and antiviral activities. It may also be used in various synthesis processes for developing novel chemical entities.

Is (2R)-1-({4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl}oxy)-2-propanol (CAS: 649735-46-6) safe?

While the exact safety profile is limited, this compound should be handled with caution due to its complex structure. Proper protective equipment, including gloves and goggles, should be worn during handling. Storage and disposal should follow standard laboratory safety protocols.

How should (2R)-1-({4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl}oxy)-2-propanol (CAS: 649735-46-6) be stored?

Store in a cool, dry place away from direct sunlight and moisture. Use airtight containers to prevent degradation. Maintain a temperature range of 15-25°C and ensure a relative humidity below 60%. Avoid exposure to heat and open flames.

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