AS-604850 | CAS No. 648449-76-7

AS-604850

Basic Information

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CAS Number

648449-76-7

Molecular Formula

C11H5F2NO4S

Molecular Weight

285.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Density

1.71

Solubility

DMSO: >10mg/mL

SMILES

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FC1(F)OC2=C(O1)C=C(\C=C1/SC(=O)NC1=O)C=C2

InChI

InChI=1S/C11H5F2NO4S/c12-11(13)17-6-2-1-5(3-7(6)18-11)4-8-9(15)14-10(16)19-8/h1-4H,(H,14,15,16)/b8-4-

InChIKey

SRLVNYDXMUGOFI-YWEYNIOJSA-N

LogP

2.332

Topological Polar Surface Area

64.63 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

468

Safety Information

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GHS Hazard Pictograms

H317

Hazard Statement

H317 May cause an allergic skin reaction
Sensitization, Skin

Synonyms & References

English

AS-604850
PI 3-Kinase Inhibitor (AS604850) B-0302
5-(2,2-Difluoro-benzo[1,3]dioxol-5-ylmethylene)-thiazolidine-2,4-dione
PI3Kγ inhibitor
PI 3-Kgamma Inhibitor II
(5E)-5-[(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)METHYLENE]-1,3-THIAZOLIDINE-2,4-DIONE
PI3Kgamma inhibitor
(5Z)-5-[(2,2-difluoro-1,3-benzodioxol-5-yl)methylidene]-1,3-thiazolidine-2,4-dione
BYM
2a4z
AS604850
PI 3-Kg inhibitor II
MLS006010996
GTPL6024
HMS3261F11
HMS3229I21
HMS3650F11
BCPP000389
Tox21_500505
s2681

MDL Number

MFCD09265247

FAQ

What is AS-604850 (CAS: 648449-76-7)?

AS-604850 is a selective and potent inhibitor of the p38 mitogen-activated protein kinase (p38 MAPK) with potential antineoplastic and anti-inflammatory activities. It is used in research to study the effects of p38 MAPK inhibition.

What are the main uses of AS-604850 (CAS: 648449-76-7)?

AS-604850 is primarily used in research to study the effects of p38 MAPK inhibition. It is also used in pharmaceutical research to develop potential antineoplastic and anti-inflammatory drugs.

Is AS-604850 (CAS: 648449-76-7) safe?

AS-604850 is generally considered safe for laboratory use when handled with appropriate precautions. However, it should be used under a fume hood and handled by trained personnel to minimize exposure risks.

How should AS-604850 (CAS: 648449-76-7) be stored?

AS-604850 should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to protect it from moisture and air exposure. Store at room temperature (15-30°C) and avoid freezing.