4-Chloro-2-methylquinazoline

Basic Information

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CAS Number

6484-24-8

Molecular Formula

C9H7ClN2

Molecular Weight

178.62 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

211.2℃ at 760 mmHg

SMILES

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CC1=NC2=CC=CC=C2C(=N1)Cl

InChI

InChI=1S/C9H7ClN2/c1-6-11-8-5-3-2-4-7(8)9(10)12-6/h2-5H,1H3

InChIKey

HAAZMOAXEMIBAJ-UHFFFAOYSA-N

LogP

2.5916200000000007

Topological Polar Surface Area

25.78 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

163

Synonyms & References

English

6484-24-8
BCP27389
AS-18674
BP-11973
4-Chloro-2-methyl-quinazoline, AldrichCPR
AKOS005145977
AM20040954
4-chloro-2-methyl-quinazoline
FT-0646430
CS-W022143
2-Methyl-4-chloroquinazoline
4-chloro-2-methylquinazoline
Cyclohexylaminehydrochloride
A15731
Z147652340
J-514974
MFCD05666292
Quinazoline, 4-chloro-2-methyl-
EN300-23231
DTXSID70382906
SY027248
HAAZMOAXEMIBAJ-UHFFFAOYSA-N
SCHEMBL856788
Quinazoline,4-chloro-2-methyl-
RP23994
HP23043
RP23996
ST2411289
AB0028210
X0260

MDL Number

MFCD05666292

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 4-Chloro-2-methylquinazoline (CAS: 6484-24-8)?

4-Chloro-2-methylquinazoline (CAS: 6484-24-8) is a crystalline compound with a molecular weight of approximately 214.01 g/mol. It has a low water solubility and is slightly soluble in organic solvents such as ethanol and acetone. The compound is relatively stable under normal conditions but can be reactive with strong acids or bases. It is generally insoluble in water.

How is 4-Chloro-2-methylquinazoline (CAS: 6484-24-8) typically synthesized?

4-Chloro-2-methylquinazoline (CAS: 6484-24-8) can be synthesized through the reaction of 2-methylquinazoline with chlorine gas in the presence of a suitable catalyst. The reaction is typically conducted under controlled conditions to achieve high yields and selectivity.

What industries use 4-Chloro-2-methylquinazoline (CAS: 6484-24-8)?

4-Chloro-2-methylquinazoline (CAS: 6484-24-8) is used in various industries including pharmaceuticals, where it serves as a precursor for drug synthesis, and in the polymer industry as a monomer for the production of certain polymers. It also finds applications in sensor technology and semiconductor manufacturing.

What precautions should be taken when handling 4-Chloro-2-methylquinazoline (CAS: 6484-24-8)?

When handling 4-Chloro-2-methylquinazoline (CAS: 6484-24-8), appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. The compound should be stored in a well-ventilated area and away from sources of heat and ignition. Spills should be handled carefully using appropriate safety measures, and the material safety data sheet (MSDS) should be consulted for specific handling instructions.