Erythromycin Stearate/Palmitate

Basic Information

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CAS Number

643-22-1

Molecular Formula

C37H67NO13.C18H36O2

Molecular Weight

1018.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

100-104°C

Solubility

ethanol: soluble50mg/mL, clear to very slightly hazy, colorless

SMILES

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CCCCCCCCCCCCCCCCCC(=O)O.CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O

InChI

InChI=1S/C37H67NO13.C18H36O2/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26;1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3;2-17H2,1H3,(H,19,20)/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-;/m1./s1

InChIKey

YAVZHCFFUATPRK-YZPBMOCRSA-N

LogP

8.11810

Complexity

1380

Safety Information

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Hazard Statement

H317 May cause an allergic skin reaction
Sensitization, Skin

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Sensitization, respiratory

Stability

Stable. Combustible. Incompatible with acids, strong oxidizing agents.

Synonyms & References

English

SR-01000872741
CS-0031206
Meberyt
Erythromycin, stearate (salt)
STEARIC ACID, COMPOUND WITH ERYTHROMYCIN (1:1)
HMS501D19
ERYTHROMYCIN STEARATE [USP MONOGRAPH]
Erythromycin, octadecanoate (salt)
ERYTHROMYCIN STEARATE (MART.)
Erythromycin stearate/ >550ug/mg
Pharmakon1600-01500281
Erythromycin stearate (USP:BAN:JAN)
Erythromycin stearate [USP:BAN:JAN]
ERYTHROMYCIN STEARATE (USP-RS)
NSC756747
ERYTHROMYCIN STEARIC ACID SALT
NSC-756747
ERYTHROMYCINI STEARAS [WHO-IP LATIN]
HMS3264B08
Q27283244
ERYTHROMYCIN STEARATE [USP IMPURITY]
CHEBI:34742
DTXCID20571
Wyamycin S
AT37747
Erythrocin
ERYTHROMYCIN STEARATE [MI]
Erythromycini stearas
Eratrex
EINECS 211-396-1
HSDB 4178

MDL Number

MFCD00084690

Customs Code

2942000000

FAQ

What are the physical and chemical properties of Erythromycin Stearate/Palmitate (CAS: 643-22-1)?

Erythromycin Stearate/Palmitate (CAS: 643-22-1) is a semi-synthetic macrolide antibiotic. It has a crystalline form with a molecular weight of approximately 1000 g/mol. The compound is poorly soluble in water but soluble in organic solvents. It is relatively stable under acidic conditions but can be hydrolyzed in basic media. It is used in pharmaceuticals and as a preservative in cosmetics.

How is Erythromycin Stearate/Palmitate (CAS: 643-22-1) typically synthesized?

Erythromycin Stearate/Palmitate is synthesized through esterification reactions. The process involves esterifying erythromycin with stearic and palmitic acids. Commonly, this is done using a strong base like sodium hydroxide or potassium hydroxide as a catalyst. The reaction is typically carried out in an alcohol solvent, producing a mixture of esters which is then purified.

What industries use Erythromycin Stearate/Palmitate (CAS: 643-22-1)?

Erythromycin Stearate/Palmitate is primarily used in the pharmaceutical industry for its antimicrobial properties. It is also used in the cosmetics industry as a preservative. Additionally, it can be used in the food industry as a stabilizer or emulsifier. Its application in polymers and as a component in some sensors or semiconductors is less common.

What precautions should be taken when handling Erythromycin Stearate/Palmitate (CAS: 643-22-1)?

When handling Erythromycin Stearate/Palmitate (CAS: 643-22-1), appropriate personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbent materials. In case of skin contact, wash with soap and water. For more detailed information, refer to the safety data sheet (SDS).