O-Benzyl-N-methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-serine | CAS No. 64263-84-9

O-Benzyl-N-methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-serine

Basic Information

CAS Number

64263-84-9

Molecular Formula

C16H23NO5

Molecular Weight

309.36 g/mol

AD

Basic Physical Properties

CC(C)(C)OC(=O)N(C)C(COCC1=CC=CC=C1)C(=O)O

InChI

InChI=1S/C16H23NO5/c1-16(2,3)22-15(20)17(4)13(14(18)19)11-21-10-12-8-6-5-7-9-12/h5-9,13H,10-11H2,1-4H3,(H,18,19)/t13-/m0/s1

InChIKey

GEKRSZPFMBQNCM-ZDUSSCGKSA-N

LogP

2.5233

Topological Polar Surface Area

76.07 Ų

Hydrogen Bond Donor/Acceptor

1 / 6

Complexity

371

Synonyms & References

English

  • Boc-N-Me-Ser(Bzl)-OH
  • boc-N-methyl serine benzyl ether
  • BS-51378
  • O-Benzyl-N-(tert-butoxycarbonyl)-N-methyl-L-serine
  • (2S)-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]-3-phenylmethoxypropanoic acid
  • SCHEMBL1374794
  • CS-0173333
  • (S)-3-(Benzyloxy)-2-((tert-butoxycarbonyl)(methyl)amino)propanoic acid
  • DTXSID20673997
  • GEKRSZPFMBQNCM-ZDUSSCGKSA-N
  • (S)-3-Benzyloxy-2-(tert-butoxycarbonyl-methyl-amino)-propionic acid
  • 64263-84-9
  • D87035
  • Boc-N-methyl-O-benzyl-L-serine
  • L-Serine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl-O-(phenylmethyl)-
  • BOC-N-ME-SER(BZL)-OH

MDL Number

MFCD00038753

FAQ

What are the physical and chemical properties of O-Benzyl-N-methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-serine (CAS: 64263-84-9)?

O-Benzyl-N-methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-serine is a white crystalline solid with a molecular weight of approximately 283.33 g/mol. It is sparingly soluble in water but soluble in organic solvents like ethanol and methanol. The compound is chemically stable under normal conditions but can react with strong nucleophiles. It is not flammable but should be stored away from strong acids and bases.

How is O-Benzyl-N-methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-serine (CAS: 64263-84-9) typically synthesized?

O-Benzyl-N-methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-serine is typically synthesized through multi-step reactions involving acylation, protection, and deprotection steps. Common catalysts include equivalents of triphenylphosphine and diisopropylcarbamoyl chloride. The synthesis involves high yields and good selectivity, making it suitable for industrial applications.

What industries use O-Benzyl-N-methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-serine (CAS: 64263-84-9)?

O-Benzyl-N-methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-serine is primarily used in the pharmaceutical and biochemical industries. It serves as a precursor in the synthesis of various pharmaceuticals and as a building block in the development of new drugs. Additionally, it has applications in the production of certain polymers and as a reagent in analytical chemistry.

What precautions should be taken when handling O-Benzyl-N-methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-serine (CAS: 64263-84-9)?

When handling O-Benzyl-N-methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-serine, it is essential to wear appropriate personal protective equipment (PPE) including gloves and safety goggles. The compound should be used in a well-ventilated area, or a fume hood to avoid inhalation. Spills should be cleaned up immediately using appropriate absorbents, and the area should be well ventilated. Always refer to the Material Safety Data Sheet (MSDS/SDS) for detailed safety information and emergency procedures.

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