Atracurium Besylate (Mixture of Isomers)

Basic Information

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CAS Number

64228-81-5

Molecular Formula

C65H82N2O18S2

Molecular Weight

1243.5 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

No data available

Melting Point

85-90 ºC

Boiling Point

218.0±23.0 °C at 760 mmHg

Flash Point

78.5±19.6 °C

Solubility

H2O: ~27 mg/mL

SMILES

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C[N+]1(CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3)OC)OC)OC)OC)CCC(=O)OCCCCCOC(=O)CC[N+]4(CCC5=CC(=C(C=C5C4CC6=CC(=C(C=C6)OC)OC)OC)OC)C.C1=CC=C(C=C1)S(=O)(=O)[O-].C1=CC=C(C=C1)S(=O)(=O)[O-]

InChI

InChI=1S/C53H72N2O12.2C6H6O3S/c1-54(22-18-38-32-48(62-7)50(64-9)34-40(38)42(54)28-36-14-16-44(58-3)46(30-36)60-5)24-20-52(56)66-26-12-11-13-27-67-53(57)21-25-55(2)23-19-39-33-49(63-8)51(65-10)35-41(39)43(55)29-37-15-17-45(59-4)47(31-37)61-6;2*7-10(8,9)6-4-2-1-3-5-6/h14-17,30-35,42-43H,11-13,18-29H2,1-10H3;2*1-5H,(H,7,8,9)/q+2;;/p-2

InChIKey

XXZSQOVSEBAPGS-UHFFFAOYSA-L

LogP

11.32610

Complexity

1560

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

对热敏感

Synonyms & References

English

HY-B0292A
NCGC00262598-01
WELLCOME 33-A-74
Q-101018
2,2'-(3,3'-(pentane-1,5-diylbis(oxy))bis(3-oxopropane-3,1-diyl))bis(1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium) benzenesulfonate
EN300-297373
Atracurii besilas
DB00732
Pentamethylen bis(3-(1,2,3,4-tetrahydro-6,7-dimethoxy-1-(3,4-dimethoxybenzyl)-2-methyl-2-isochinolyl)propionat) bis(benzolsulfonat)
Atracurium for peak identification, European Pharmacopoeia (EP) Reference Standard
CHEMBL1200527
XXZSQOVSEBAPGS-UHFFFAOYSA-L
Tracrium (TN)
Atracurium besylate
HMS2095A11
NSC-760047
SR-01000781272
Besilato de atracurio
DTXSID6022630
2-(2-Carboxyethyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-veratrylisoquinolinium benzenesulfonate, pentamethylene ester
Q-200864
SCHEMBL41251
2,2'-[1,5-Pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-isoquinolinium Benzenesulfonate
atracurio besilato
Besilate d'atracurium [INN-French]
Atracurium besylate [USAN:USP]
NSC760047
NS00086140
benzenesulfonate; 5-[3-[(1R,2R)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl 3-[(1S,2S)-1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propan
Atracurium for impurity F identification, European Pharmacopoeia (EP) Reference Standard
2,2'-((pentane-1,5-diylbis(oxy))bis(3-oxopropane-3,1-diyl))bis(1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium)benzenesulfonate

MDL Number

MFCD00797403

FAQ

What is Atracurium Besylate (Mixture of Isomers) (CAS: 64228-81-5)?

Atracurium Besylate (Mixture of Isomers), with the CAS number 64228-81-5, is a non-depolarizing neuromuscular blocking agent used in medical settings. It is a mixture of isomers of the drug atracurium, which is commonly administered during surgeries to induce muscle relaxation. The compound has a molecular formula of C23H41N3O12S2 and is known for its rapid onset and short duration of action, making it suitable for short procedures. It is typically available as a sterile solution for intravenous use.

What are the main uses of Atracurium Besylate (Mixture of Isomers) (CAS: 64228-81-5)?

Atracurium Besylate (Mixture of Isomers) is primarily used in anesthesia to provide muscle relaxation during surgical procedures. It is particularly favored for its quick onset and short duration, allowing for easier recovery. The compound is also used in research to study neuromuscular function and in the pharmaceutical industry for drug development. Its applications include facilitating intubation and reducing the risk of postoperative respiratory complications.

Is Atracurium Besylate (Mixture of Isomers) (CAS: 64228-81-5) safe?

Atracurium Besylate (Mixture of Isomers) is generally considered safe when used as directed in medical settings. It is well-tolerated by most patients and has a favorable safety profile compared to other neuromuscular blocking agents. However, like all medications, it should be handled with care, and healthcare professionals must follow proper safety protocols to minimize risks. Precautions include monitoring for adverse effects such as hypotension and ensuring appropriate dosing to avoid toxicity.

How should Atracurium Besylate (Mixture of Isomers) (CAS: 64228-81-5) be stored?

Atracurium Besylate (Mixture of Isomers) should be stored in a cool, dry place away from direct light. It is typically kept at a temperature between 2°C to 8°C (36°F to 46°F) and should not be exposed to extreme heat or humidity. The container should be tightly sealed and protected from moisture to maintain stability and potency. Always check the expiration date and follow manufacturer guidelines for storage conditions.