2,6-Dichloro-3-methylaniline

Basic Information

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CAS Number

64063-37-2

Molecular Formula

C7H7Cl2N

Molecular Weight

176.05 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

37-40 ºC

Boiling Point

241.1℃/760mmHg

Density

1.3789 (rough estimate)

Flash Point

0℃

Refractive Index

1.5690 (estimate)

SMILES

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CC1=C(C(=C(C=C1)Cl)N)Cl

InChI

InChI=1S/C7H7Cl2N/c1-4-2-3-5(8)7(10)6(4)9/h2-3H,10H2,1H3

InChIKey

AYVZXDFCFQSWJD-UHFFFAOYSA-N

LogP

2.8840200000000005

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

118

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

I10185
W-104862
CHEMBL3184053
MFCD00007676
Tox21_302255
NS00035629
SCHEMBL1638904
PS-3506
2,6-dichloro-3-methyl aniline
2,6-Dichloro-m-toluidine
AKOS000120231
Q27289778
64063-37-2
SY005706
FT-0610617
DTXSID7044710
AMY14633
NCGC00256029-01
DTXCID5024710
AC-18002
3-Amino-2,4-dichlorotoluene
2,6-Dichloro-3-methylbenzenamine
DS-1645
InChI=1/C7H7Cl2N/c1-4-2-3-5(8)7(10)6(4)9/h2-3H,10H2,1H
2,6-dichloro-3-methylphenylamine
2,6-Dichloro-3-methylaniline
A834627
EINECS 264-649-3
T7QD52545O
CAS-64063-37-2
Benzenamine, 2,6-dichloro-3-methyl-

MDL Number

MFCD00007676

FAQ

What are the physical and chemical properties of 2,6-Dichloro-3-methylaniline (CAS: 64063-37-2)?

2,6-Dichloro-3-methylaniline is a crystalline solid with a molecular weight of approximately 213.03 g/mol. It has a high melting point of 122-124°C and is slightly soluble in water. The compound exhibits good reactivity with electrophiles and is used in organic synthesis due to its ability to form stable intermediates. It is also known for its aromatic character and reactive chlorine groups.

How is 2,6-Dichloro-3-methylaniline (CAS: 64063-37-2) typically synthesized?

2,6-Dichloro-3-methylaniline is commonly synthesized through the reaction of 3-methylaniline with chlorine gas in the presence of a Lewis acid catalyst like aluminum chloride. The reaction is exothermic and requires careful temperature control to ensure selectivity. High yields and purity are attainable with appropriate conditions.

What industries use 2,6-Dichloro-3-methylaniline (CAS: 64063-37-2)?

2,6-Dichloro-3-methylaniline is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various medicines. It also finds applications in the production of dyes, pesticides, and other chemical products. Its reactivity with chlorine makes it valuable in industries requiring specialized organic compounds.

What precautions should be taken when handling 2,6-Dichloro-3-methylaniline (CAS: 64063-37-2)?

When handling 2,6-Dichloro-3-methylaniline, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately with appropriate absorbents and flushed with water. Always consult the Safety Data Sheet (SDS) for detailed safety guidelines.