1-[(Benzyloxy)carbonyl]-D-proline

Basic Information

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CAS Number

6404-31-5

Molecular Formula

C13H15NO4

Molecular Weight

249.27 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

74.0 to 78.0 deg-C

Boiling Point

432.3°C at 760 mmHg

Density

1.3090

Flash Point

215.3±28.7 °C

Refractive Index

40 ° (C=2, EtOH)

Vapor Pressure

0.0±1.1 mmHg at 25°C

Specific Rotation

40 º (c=2, EtOH)

SMILES

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OC(=O)[C@H]1CCCN1C(=O)OCc2ccccc2

InChI

InChI=1S/C13H15NO4/c15-12(16)11-7-4-8-14(11)13(17)18-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,15,16)/t11-/m1/s1

InChIKey

JXGVXCZADZNAMJ-LLVKDONJSA-N

LogP

1.8722

Topological Polar Surface Area

66.84 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

312

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

N-Benzyloxycarbonyl-D-proline
1-[(Benzyloxy)carbonyl]pyrrolidine-2-carboxylic acid
N-CBZ-D-Proline
(+)-Z-D-proline
Z-D-Proline
Z-D-Pro-OH
N-Carbobenzoxy-D-proline
(2R)-1-phenylmethoxycarbonylpyrrolidine-2-carboxylic acid
(R)-1-((Benzyloxy)carbonyl)pyrrolidine-2-carboxylic acid
(R)-N-BENZYLOXYCARBONYLPROLINE
Benzyloxycarbonyl-D-proline
CBZ-D-PRO-OH
N-(Benzyloxycarbonyl)-D-proline
Zinc sulfate heptahydrate
1-[(benzyloxy)carbonyl]-d-proline
(2R)-1-[(benzyloxy)carbonyl]pyrrolidine-2-carboxylic acid
1-Benzyl hydrogen (R)-pyrrolidine-1,2-dicarboxylate
(R)-1-(BENZYLOXYCARBONYL)PYRROLIDINE-2-CARBOXYLIC ACID
N-Carb
N-Cbz-D-proline
(2R)-1-benzyloxycarbonylpyrrolidine-2-carboxylic acid

MDL Number

MFCD00063228

FAQ

What is 1-[(Benzyloxy)carbonyl]-D-proline (CAS: 6404-31-5)?

1-[(Benzyloxy)carbonyl]-D-proline (CAS: 6404-31-5) is an amino acid derivative with a benzyloxycarbonyl group attached to the alpha-carbon of D-proline. It is used in pharmaceuticals and research for its protective and reactive properties.

What are the main uses of 1-[(Benzyloxy)carbonyl]-D-proline (CAS: 6404-31-5)?

1-[(Benzyloxy)carbonyl]-D-proline (CAS: 6404-31-5) is primarily used in the synthesis of peptides and proteins. It serves as a protecting group, stabilizing the structure of amino acids during chemical modifications or purification processes.

Is 1-[(Benzyloxy)carbonyl]-D-proline (CAS: 6404-31-5) safe?

1-[(Benzyloxy)carbonyl]-D-proline (CAS: 6404-31-5) is generally safe when handled with appropriate protective measures. Users should avoid contact with skin and eyes, and ensure proper ventilation during use. Use in a well-ventilated area and wear gloves and goggles as necessary.

How should 1-[(Benzyloxy)carbonyl]-D-proline (CAS: 6404-31-5) be stored?

1-[(Benzyloxy)carbonyl]-D-proline (CAS: 6404-31-5) should be stored in a cool, dry place, protected from light and moisture. Store it in a tightly sealed container to prevent degradation. Maintain temperatures below 25°C (77°F) and avoid direct sunlight or high heat sources.